Cadherins: Types, Structure and Functions

Jonathan McWilliam (Editor)

Series: Cell Biology Research Progress
BISAC: SCI017000



Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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Cadherins are adhesion molecules which mediate homophilic Ca2+-dependent intercellular adhesion. They play a crucial role in tissue morphogenesis during embryonic development and in the maintenance of tissue architecture in adults.

In this compilation, the authors review and discuss the structure of the cadherin-mediated junctions in seminiferous tubules and their functions in male fertility.

Additionally, role of E-cadh in uterine and mammary gland homeostasis is reviewed, and the disruptive patterns of E-cadh expression in neoplastic conditions of the uterus and mammary glands in humans and domestic dogs and cats are described. (Imprint: Nova)


Chapter 1. Standing out from the Crowd: Functions of T-Cadherin in Health and Disease
(Maria Philippova, PhD, and Therese J. Resink, PhD, Tissue Engineering Laboratory, Departments of Biomedicine and Surgery, Basel University Hospital, Basel, Switzerland, and others)

Chapter 2. Cadherin-Mediated Cell Adhesion within the Seminiferous Tubules
(Rita Payan-Carreira and Dario Santos, Mediterranean Institute for Agriculture, Environment and Development, Universidade de Évora, Évora, Portugal, and others)

Chapter 3. Disruption of E-Cadherin Pattern in Uterine and Mammary Tumours
(Adelina Gama, Fernanda Seixas, Maria dos Anjos Pires, Fernando Schmitt and Rita Payan-Carreira, CECAV, Universidade de Trás-os-Montes e Alto Douro, Vila Real, Portugal, and others)


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