Buprenorphine: Pharmacology, Clinical Uses and Potential Side Effects

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Rosalina Bennet (Editor)

Series: Pharmacology – Research, Safety Testing and Regulation
BISAC: MED058170

Buprenorphine was introduced in the United States as an injectable analgesic in 1981 and as a treatment option for opioid dependence in 2002; a transdermal formulation was approved for pain management in 2010. Following the introduction of this variety of dosage forms, buprenorphine use and misuse have increased significantly. This book begins by reviewing the pharmacology of buprenorphine and co-ingredient naloxone; its use in addiction medicine and pain management; and clinical challenges, with special emphasis on drug-drug interactions (pharmacokinetic and pharmacodynamic), safety concerns, and buprenorphine misuse. The book continues to discuss the role of buprenorphine as an analgesic; the application of buprenorphine in acute and chronic pancreatitis; and the substitution maintenance treatment of opioid dependence with buprenorphine and naloxone. (Imprint: Nova)

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Table of Contents

Preface

Chapter 1. Buprenorphine: Clinical Use, Abuse and Compliance Monitoring
Anne Z. DePriest (Aegis Sciences Corporation, Nashville, and The University of Tennessee Health Science Center, College of Pharmacy, Memphis, Tennessee, USA), Katie Miller (Aegis Sciences Corporation, Nashville, and The University of Tennessee Health Science Center, College of Pharmacy, Memphis, Tennessee, USA) and Edward J. Cone, Ph.D. (Johns Hopkins School of Medicine, Department of Psychiatry and Behavioral Sciences, Baltimore, Maryland, USA)

Chapter 2. The Emerging Role of Buprenorphine As an Analgesic
Mellar P. Davis (Professor of Medicine, Division of Solid Tumor Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, USA)

Chapter 3. Buprenorphine
K. Vermeylen and F. Van de Perck (Department of Anesthesia, Turnhout, Belgium)

Chapter 4. The Application of Buprenorphine in Acute and Chronic Pancreatitis
Wenbo Meng, Bo Li, Yan Li, Shaozhen Rui, Wence Zhou and Xun Li (Special Minimally Invasive Surgery, the First Hospital of Lanzhou University, Lanzhou, Gansu, China)

Chapter 5. Substitution Mainteinance Treatment of Opioid Dependence with Buprenorphine/Naloxone Method As Prevention of Social Excluding of Young People: Tuzla Model (pp. 173-194)
Mevludin Hasanović, Izet Pajević, Abdurahman Kuldija, Amra Delić, Alija Sutović and Esmina Avdibegović (Department of Psychiatry, University Clinical Center Tuzla, Tuzla, Bosnia-Herzegovina)

Index

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