Breast Cancer: Causes, Diagnosis and Treatment


Martin E. Romero (Editor)
Louis M. Dashek (Editor)

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: MED062000

Breast cancer is often initiated by abnormal cellular mechanisms and damage to DNA brought about by different types of cellular stress. This book reviews the current standards of pathological assessment of breast cancer specimens. There is a discussion of recent molecular profiling studies in breast cancer and how our view of the classification of breast cancer is changing. The current role of molecular tests in the management of breast cancer is also addressed, highlighting their strengths and limitations. Additionally, it is widely acknowledged that the extracellular matrix (ECM) of connective tissues plays active roles in numerous biological processes such as cell differentiation, life/death promotion and carcinogenesis. The studies on embryo-foetal collagen type (OF/LB) and type V collagens are discussed and their putative relevance in ductal infiltrating carcinoma (DIC) ingrowth. This book also assesses the level and determinants of knowledge about, and risk factors for, breast cancer among women in the child bearing period. A review of the literatures regarding the injection sites of tracers in breast cancer sentinel lymph node (SLN) biopsy is examined as well. (Imprint: Nova Medicine and Health)

Table of Contents

Table of Contents


MicroRNAs in Breast Cancer (Marc Lacroix, InTextoResearch, Baelen, Belgium)

Breast Cancer and Autophagy (L.J. Armstrong, S.M. Gorski, The Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada and others)
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The Evolving Role of Molecular Markers in the Diagnosis of Breast Cancer (Danh Tran-Thanh, Susan J. Done, Department of Pathology, University Health Network, Toronto, Ontario, Canada and others)

Collagen Changes in the Extracellular Matrix of Tumor-Affected Human Breast: A Tale of OF/LB and Type V Collagens (Claudio Luparello, Dipartimento di Biologia Cellulare e dello Sviluppo, Università, Viale delle Scienze, Palermo, Italy)

Breast Cancer Knowledge and Risk Factors Assessment at Primary Health Care Setting in Al Hassa, KSA. (Tarek Tawfik Amin, Amira Gamal Abdul Rahman Community Medicine, Faculty of Medicine, Cairo University, Egypt and others)

Maspin and Cathepsin D Partnership in Regulating Mammary Gland Development and Breast Cancer (Zhila Khalkhali-Ellis, Ming Zhang, Mary J.C. Hendrix, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois and others)

Subareolar Injection May Not Always Identify the Same Sentinel Lymph Nodes as Peritumoral Injection in Breast Cancer (Masakuni Noguchi, Department of Breast Oncology, Kanazawa University Hospital, Kanazawa, Japan)

Immuno-Conjugates: New Prospects on Old Principles (M.F. Barginear, D.R. Budman, The Tisch Cancer Insitute, The Mount Sinai School of Medicine, New York, NY, and others)


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