Botulinum Toxin: Therapeutic Uses, Procedures and Efficacy

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James C. Lark (Editor)

Series: New Developments in Medical Research
BISAC: MED056000

Botulism is a serious illness whose symptoms include difficulty speaking and paralysis. The disease is caused by botulinum toxin, a neurotoxic protein produced by the bacterium Clostridium botulinum, and while the disease can be fatal, intensive treatment can prevent death in most cases. However, botulinum toxin can also be used as treatment for various illnesses when applied in correct doses. This volume includes four chapters that describe various therapeutic uses of botulinum toxin. Chapter One reviews the mechanism of action, therapeutic uses, best practices, current applications, effectiveness and available evidence of botulinum toxin application in various musculoskeletal disorders. Chapter Two focuses on the technical aspects of botulinum toxin use for treatment of sialorrhea and reported outcomes. Chapter Three describes the use of botulinum toxin as treatment for hyperkinetic movement disorders including blepharospasm, oromandibular dystonia, and hemifacial spasm. Lastly, Chapter Four deals with the use of botulinum toxin for treatment of hemimasticatory and hemifacial spasm in scleroderma.

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Table of Contents

Preface

Chapter 1. Applications of Botulinum Toxin in Musculoskeletal Disorders
Eduardo Freitas Ferreira, Catarina Peixoto, André Ladeira, Ana Filipa Neves, Isabel Pereira and Leonor Prates
Physical Medicine and Rehabilitation Department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal

Chapter 2. Botulinum Toxin: Treatment of Sialorrhea
Rodrigo Correia¹ Catarina Peixoto², Ana Filipa Gonçalves¹, André Borges¹ and José Luís de Carvalho¹
¹Physical Medicine and Rehabilitation Department, Centro de Reabilitação do Norte, Vila Nova de Gaia, Portugal
²Physical Medicine and Rehabilitation Department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal

Chapter 3. Botulinum Toxin: Treatment of Blepharospasm, Oromandibular Dystonia and Hemifacial Spasm
Catarina Peixoto, Eduardo Freitas Ferreira, Ana Filipa Neves, André Ladeira and Leonor Prates
Physical Medicine and Rehabilitation Department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal

Chapter 4. Hemimasticatory and Hemifacial Spasm in Scleroderma: Use of Botulinum Toxin
L. M. Alvis – Department of Neurology, Worcester Royal Hospital, Worcester, UK

Bibliography

Index

Additional information

Binding

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