Bisphenol A: Sources, Risks of Environmental Exposure and Human Health Effects


Yann Gibert, PhD (Editor)
Deakin School of Medicine Metabolic Research Unit, Australia

Series: Biochemistry Research Trends
BISAC: SCI007000

This book reviews the latest venues in bisphenol A (BPA) studies related to human health. BPA, a synthetic compound primarily used to make plastic, is found in many daily products making this compound almost impossible to avoid. BPA can mimic naturally occurring hormones in humans that will be mistaken by our bodies as a proper hormone leading to a wide range of endocrine defects. BPA exposure has raised a number of concerns in the public domain due to numerous studies reporting a plethora of diseases and health conditions that can be directly linked to BPA contamination.

This book conveys in a comprehensive manner to the reader the history of BPA; its adverse effects upon exposure, the novel ways to assess its levels in human samples, the non-canonical signalling pathways via which it acts on the human body and the effects induced by BPA exposure upon a variety of human organs and tissues (the immune system, adipose tissue and tooth). This is conveyed using knowledge ascertained from current research on BPA and human health. Contributors to this book are from eight different research laboratories specialized in BPA studies located in seven different countries (Australia, France, Portugal, Belgium, Canada, China and Malaysia).
(Imprint: Nova)

Table of Contents

Table of Contents


Chapter 1 – Introduction: Bisphenol A Exposure and Human Health (pp. 1-12)
Prusothman Yoganantharajah and Yann Gibert (Metabolic Genetic Diseases Laboratory, Metabolic Research Unit, Deakin School of Medicine, VIC, Australia)

Chapter 2 – Potential Applications and Adverse Effects of Bisphenol A in Humans (pp. 13-32)
A. H. Bhat, Y. K. Dasan, I. U. Haque and A. Ahmad (Department of Fundamental and Applied Sciences, Universiti Teknologi Petronas, Perak, Malaysia and others)

Chapter 3 – BPA Evaluation in Human Samples (pp. 33-124)
Luísa Correia-Sá, Conceição Calhau, Cristina Delerue-Matos and Valentina Fernandes Domingues (REQUIMTE, Instituto Superior de Engenharia, Instituto Politécnico do Porto, Rua Drº António Bernardino de Almeida, Porto; Department of Biochemistry (U38-FCT), Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, Porto, and CINTESIS – Center for Research in Health Technologies and Information Systems, Porto, Portugal)

Chapter 4 – Human Exposure of Bisphenol A: Review of the Urinary Biomarker Levels in the General Population (pp. 125-154)
Catherine Pirard and Corinne Charlier (Laboratory of Clinical, Forensic and Environmental Toxicology, University of Liege (ULg), Liege, Belgium)

Chapter 5 – BPA Signaling through Non-Canonical Receptors (pp. 154-180)
Vincent Laudet and Gabriel Livera (Institut de Génomique Fonctionnelle de Lyon, Université de Lyon, Université Lyon 1, Centre National de la Recherche Scientifique (CNRS), Ecole Normale Supérieure de Lyon, 46 allée d’Italie, 69364 Lyon CEDEX 07, and Laboratory of Development of the Gonads, Unit of Stem Cells and Radiation, Univ. Paris Diderot, Sorbonne Paris Cité; Univ Paris Sud; INSERM, UMR 967; CEA, DSV, iRCM, SCSR, LDG; route du Panorama – BP 6, 92265 Fontenay aux Roses Cedex, France)
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Chapter 6 – Early-Life Exposure of Bisphenol A and Obesity (pp. 181-204)
Kirstie A. De Jong, Ken Walder and Yann Gibert (Metabolic Research Unit, Deakin School of Medicine, VIC, Australia)

Chapter 7 – The Tooth, Target Organ of Bisphenol A, Could Be Used As a Biomarker of Exposure to This Agent (pp. 204-226)
Katia Jedeon, Ariane Berdal and Sylvie Babajko (Centre de Recherche des Cordeliers, INSERM UMRS 1138, Laboratory of Molecular Oral Pathophysiology, Paris; Université Paris-Descartes, Paris; Université Pierre et Marie Curie-Paris, Paris, and Université Paris-Diderot, UFR d’Odontologie, F-75006, Paris, and Centre de Référence des maladies rares de la face et de la cavité buccale MAFACE hôpital Rothschild, AP-HP, Paris, France)
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Chapter 8 – Immune Functions and Consequences of Bisphenol-A Exposure (pp. 227-248)
James A. Rogers and V. Wee Yong (Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada)

Chapter 9 – Influence of Bisphenol on Developing Rat Estrogen Receptors and Some Cytokines in Rats: A Two-Generational Study (pp. 249-262)
Z. X. Gao, S. Miao and N. Liu (Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Tianjin Institute of Health and Environmental Medicine, P. R. China, and Medical Laboratory Department, Shandong Medical College, Jinan, China)


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