Biological Activity of Natural Products

Jaroslava Švarc-Gajić
Faculty of Technology, Novi Sad, Serbia

Series: Biochemistry Research Trends
BISAC: MED032000

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Many thousands of years ago, humans were introduced to the toxicants of minerals and plants of microbial origin, and since that time, natural bioactive compounds have been used in traditional medicine for treating different health conditions, but also as aphrodisiacs and as a means of suicide or murder. Modern medicine acknowledges natural bioactive compounds as valuable medicinal sources for both diagnostic and curative purposes. Natural compounds serve as templates for the production of new drugs with improved pharmacological properties.

This book explains the term bioactivity and deals with the bioactive compounds of plants, animals, microbial and marine origin. Their use by traditional medicinal approach, as well as by modern medicine is further elaborated. Both beneficial and toxic properties of different chemical classes, including alkaloids, peptides, terpenoids, bioactive amines etc., are described. Their isolation at the industrial scale is presented through several technological processes which are explained in detail for several compound classes.

The research explains how natural sources can be exploited my modern and traditional medicine, and presents the risks and benefits associated with their use. In addition, a new approach to studying bioactivity, that includes computational modeling and software for in silico description and prediction, is explained. A chemometric approach to studying bioactivity is demonstrated through several models given for some natural bioactive compounds and their derivatives. (Imprint: Novinka )

Preface pp.vii-viii

Introduction pp.ix-x

Chapter I. Bioactivity and Toxicity pp.1-14

Chapter II. Natural Bioactive Compounds pp.15-32

Chapter III. Medicinal Use of Some Phytochemicals pp.33-44

Chapter IV. Medicinal Use of Alkaloids pp.45-56

Chapter V. Adverse Effects of Natural Phenols pp.57-74

Chapter VI. Risks Associated with Bioactive Food Ingredients pp.75-92

Chapter VII. Medicinal Use of Venoms pp.93-110

Chapter VIII. Chemometry of Natural Compounds pp.111-132

Index pp.133-137

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