Bioactive Materials in Dentistry: Remineralization and Biomineralization

Francine Benetti, PhD (Editor)
Department of Restorative Dentistry, São Paulo State University (Unesp), School of Dentistry, Araçatuba, São Paulo, Brazil

Series: Dentistry and Oral Sciences
BISAC: MED016000

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Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Bioactive materials, or biomaterials, have the ability to interact biologically with the tissue to which it is inserted, and to stimulate the deposition of mineralized tissue. The calcium phosphate-based ceramics were the first known materials in dentistry to have bioactivity, and currently, these materials are the most used for biomedical purposes, with different morphological characteristics. In dentistry, these materials have achieved immense importance by stimulating the deposition of osseous tissue in injured bone, and by having the ability to remineralize hard tooth tissues (enamel and dentin).

Furthermore, repair materials based on aggregated trioxides mineral or on calcium hydroxide are classic biomaterials and widely used in dentistry, mainly in contact with the pulp tissue or periodontal ligament, for repair processes. However, various formulations of these materials appear all the time, in search of the ideal material. In general, bioactive materials have been shown to promote the release of calcium, sodium, silicon and phosphate ions, which are metabolized by the body, having effects such as angiogenesis and antimicrobial action, which can be improved depending on the composition of the material. Pulp tissue is a highly specialized dental tissue and is the subject of intense studies about the response to biomaterials. It is also understood that some systemic alterations in individuals have an influence on the action of bioactive materials during tissue repair processes.

Thus, this book will address the use of different bioactive materials in dentistry, considering the performance of these biomaterials in the hard tissues of the tooth, and the response of the dental pulp, as well as the influence of the composition of these materials and of the individual’s systemic alterations in bioactivity and in antimicrobial activity. The several in vivo and in vitro tests to evaluate the bioactivity of a biomaterial will also be addressed.
(Imprint: Nova Medicine and Health)

Preface

Chapter 1. Remineralizing Performance of Different Materials on Teeth Hard Tissues
(Marjorie de O. Gallinari, M.Sc.; Luciano T. A. Cintra, Ph.D.; Carlos R. E. Bueno, M.Sc.; André L. F. Briso, Ph.D.; Gustavo Sivieri de Araújo, Ph.D.; Vanessa A. S. Marques, M.Sc., and Francine Benetti, Ph.D, Department of Restorative Dentistry, São Paulo State University (Unesp), School of Dentistry, Araçatuba, SP, BR and Department of Endodontics, São Paulo State University (Unesp), School of Dentistry, Araçatuba, SP, BR)

Chapter 2. Current Methodologies for Evaluating Remineralization and Biomineralization in Dentistry
(Letícia C. Conti, M.Sc.; Vanessa A. S. Marques, M.Sc.; Luciano T. A. Cintra, Ph.D.; Rogério de C. Jacinto, Ph.D.; Marjorie de O. Gallinari, M.Sc.; Marina T. Souza, Ph.D.; and Francine Benetti, Ph.D., Department of Endodontics, São Paulo State University (Unesp), School of Dentistry, Araçatuba, SP, BR and Department of Restorative Dentistry, São Paulo State University (Unesp), School of Dentistry, Araçatuba, SP, BR; Department of Materials Engineering, Federal University of São Carlos, SP, BR)

Chapter 3. Bioceramic Materials
(Carlos R. E. Bueno, M.Sc.; Luciano T. A. Cintra, Ph.D.; Francine Benetti, Ph.D.; Renan Dal Fabbro, M.Sc.; Rogério de C. Jacinto, Ph.D.; and Elói Dezan-Júnior, Ph.D., Department of Endodontics, São Paulo State University (Unesp), School of Dentistry, Araçatuba, SP, BR)

Chapter 4. Antimicrobial Activity of Bioactive Materials
(Carlos R. E. Bueno, M.Sc.; Leopoldo Cosme-Silva, M.Sc.; Francine Benetti, Ph.D.; Elói Dezan-Júnior, Ph.D.; Luciano T. A. Cintra, Ph.D.; Paulo C. T. Duarte, Ph.D.; and Rogério de C. Jacinto, Ph.D., Department of Endodontics, São Paulo State University (Unesp), School of Dentistry, Araçatuba, SP, BR and Health Department, Area of Pediatric Dentistry, State University of Feira de Santana (UEFS), Feira de Santana, BA, BR)

Chapter 5. The Dental Pulp & Bioactive Materials
(Paulo C. T. Duarte, Ph.D.; Luciano T. A. Cintra, Ph.D.; Carlos R. E. Bueno, M.Sc.; Leopoldo Cosme-Silva, M.Sc.; João E. Gomes-Filho, Ph.D.; Elói Dezan-Júnior, Ph.D.; and Francine Benetti, Ph.D., Health Department, Area of Pediatric Dentistry, State University of Feira de Santana (UEFS), Feira de Santana, BA, BR and Department of Endodontics, São Paulo State University (Unesp), School of Dentistry, Araçatuba, SP, BR)

Chapter 6. Systemic Alterations and Different Tissue Response to Bioactive Materials
(Renan Dal Fabbro, M.Sc.; Leopoldo Cosme-Silva, M.Sc.; Francine Benetti, Ph.D.; Gustavo Sivieri de Araújo, Ph.D.; Letícia C. Conti, M.Sc.; João E. Gomes-Filho, Ph.D.; and Luciano T. A. Cintra, Ph.D., Department of Endodontics, São Paulo State University (Unesp), School of Dentistry, Araçatuba, SP, BR)

Chpater 7. Bioactive Glasses Composition and the Influence on Remineralization and Biomineralization
(Marina T. Souza, Ph.D.; Francine Benetti, Ph.D.; Luciano T. A. Cintra, Ph.D.; Edgar D. Zanotto, Ph.D., Department of Materials Engineering, Federal University of São Carlos, SP, BR; and Department of Endodontics, São Paulo State University (Unesp), School of Dentistry, Araçatuba, SP, BR)

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