Bioactive Glasses: Properties, Composition and Recent Applications


Daniel Arcos
Maria Vallet-Regi
Department of Chemistry in Pharmaceutical Sciences
Faculty of Pharmacy, Universidad Complutense de Madrid
Madrid, Spain

Series: Materials Science and Technologies
BISAC: TEC021000

More than 50 years have passed since Professor Larry L. Hench discovered Bioglass. However bioactive glasses still awake the fascination of scientists, lecturers, students, dentists, orthopedic surgeons, etc. all over the world. The research developed during the subsequent decades has resulted in new materials that significantly differ from the original melt-derived Bioglass. The use of the sol-gel process in the 1990’s and the discovery of mesoporous bioactive glasses in the 2000’s revealed new potential applications in the field of bone regeneration and drug delivery platforms. Besides, the development of rapid prototyping techniques has allowed manufacturing bioglass-based 3D scaffolds in combination with polymers, which boosts the long-standing expectative of using bioactive glasses for the treatment of critical bone defects. Finally, the advances in nanomedicine have opened new research lines involving the synthesis and development of bioactive glass nanoparticles. “Bioactive Glasses: Properties, Composition and Recent Applications” consists of ten chapters written be worldwide recognized experts in this field. The book covers the most important topics in the field of bioactive glasses, from its discovering to the most recent advances in preparation methods and applications. This book is addressed to researchers involved in the field of bioceramics, but it also an excellent tool for undergraduate and PhD students, given that nowadays Biomaterials Science is a subject included in the program of many universities. Only knowing the discoveries that fifty years ago fascinated us, our students will understand the current efforts to expand the applications of bioactive glasses.



Table of Contents


Chapter 1. Bioglass and Bioactivity: A Brief Look Back
(David C. Greenspan, Spinode Consulting, Florida, US)

Chapter 2. Bioactive Glasses and Their Applications in Bone Tissue Engineering
(Chris Steffi and Wilson Wang, Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore)

Chapter 3. Composition-Bioactivity Correlations of Bioactive Glasses From a Structural Perspective
(Mattias Edén, Physical Chemistry Division, Department of Materials and Environmental Chemistry,
Stockholm University, Stockholm, Sweden)

Chapter 4. Phosphate-Based Glasses: From Structural Specificities to Targeted Biomedical Applications
(Jérémy Soulié, CIRIMAT, CNRS, INP- ENSIACET, Université de Toulouse, Toulouse, France)

Chapter 5. Antibacterial Properties of the Bioactive Glass S53P4 Bone Substitute and Its Clinical Use in Infection Treatment
(Nina Lindfors, Department of Musculoskeletal and Plastic Surgery, Helsinki University Hospital, Helsinki University, Helsinki, Finland)

Chapter 6. Synthesis, Composition, and Properties of Bioactive Glass Nanoparticles
(Kai Zheng, Usanee Pantulap and Aldo R. Boccaccini, Institute of Biomaterials, University of Erlangen-Nuremberg, Erlangen, Germany)

Chapter 7. Mesoporous Bioactive Glasses: State of the Art and Future Prospects
(Antonio J. Salinas, Department Chemistry in Pharmaceutical Sciences, Universidad Complutense [UCM], Madrid, Spain, and others)

Chapter 8. Cell Responses to Mesoporous Bioactive Glasses
(María Teresa Portolés and Laura Casarrubios, Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos [IdISSC], Madrid, Spain)

Chapter 9. Mesoporous Bioglass Composite Scaffolds for Bone Tissue Engineering
(Yufang Zhu, Ziyan Huang, Tian Li and Chengtie Wu State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, P. R. China)

Chapter 10. Hybrid Formulations Based on Mesoporous Bioactive Glasses/Polymer Phases for the Design of Bone Scaffolds and Delivery Platforms
(Sonia Fiorilli, Carlotta Pontremoli, Giorgia Montalbano and Chiara Vitale Brovarone, Department of Applied Science and Technology, Politecnico di Torino, Torino, Italy)


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