Beta-Lactamases: An Overview

Thomas E. Stead (Editor)

Series: Microbiology Research Advances
BISAC: SCI045000



Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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In this compilation, the authors describe the occurrence and characteristics of ESBL/AmpC-producing Enterobacteriaceae in poultry, cattle and pigs, pointing to risk factors that lead to their spread and highlighting possible mitigation strategies that could be applied to reduce their prevalence in food-producing animals.

One review focuses on the wide array of antimicrobial resistance mechanisms that have been described in A. baumannii. The most concerning ones being the β-lactamases with carbapenemase activity, i.e, Ambler class-D serine oxacillinases and Ambler class-B metallo-β-lactamases.

The closing study will walk readers through the discovery and golden age of β-lactam, its mechanism of action as broad-spectrum antibiotic, the expansion of beta-lactam derivatives and β-lactamase inhibitors to antibiotic resistance in β-lactams.
(Imprint: Nova)


Chapter 1. The Emergence and Evolution of Extended-Spectrum β-Lactamases (ESBL) and AmpC in Food-Producing Animals, Farm Environment and Their Products
(Jungwhan Chon, PhD, Dongryeoul Bae, PhD, Saeed Khan, PhD, and Kidon Sung, PhD, Division of Microbiology, National Center for Toxicological Research, and others)

Chapter 2. Resistance Mechanisms in Acinetobacter with an Emphasis on β-Lactamases: An Update
(Ritika Chauhan and Jayanthi Abraham, Microbial Biotechnology Laboratory, SBST, VIT University, Vellore, Tamil Nadu, India)

Chapter 3. Golden Age of β-Lactam Antibiotics to Antibiotic Resistance
(Aparna Shivaprasad, PhD, and Beena Antony, PhD, Department of Microbiology, MV Jayaram Medical College, Bengaluru, India, and others)


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