Benzothiazole: Preparation, Structure and Uses

Atakan Heijstek (Editor)

Series: Chemistry Research and Applications
BISAC: SCI013040



Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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Benzothiazole is an aromatic heterocyclic compound with the chemical formula of C7H5NS. Benzothiazole: Preparation, Structure and Uses opens with a review on the synthesis of benzothiazoles for their anticancer, antimicrobial, antidiabetic, anticonvulsant, anti-inflammatory, anthelmintic, analgesic, antiviral and antitubercular activities.

Following this, considering the versatile nature of benzothiazole, various benzothiazole derivatives with anticonvulsant and anticancer activity are discussed in detail.

A report on the design strategies, detailed photo-physical properties and applications of benzothiazoles is provided in an effort to help researchers overcome existing challenges in designing novel excited state intramolecular proton transfer benzothiazole fluorescent molecules.

In closing, the authors present recent updates on the usefulness and structure-activity relationship of benzothiazole derivatives for the development of novel anticancer agents.
(Imprint: Nova)


Chapter 1. Synthesis of Benzothiazoles
(Syed Shafi and Ahmed Kamal, Department of Pharmaceutical Chemistry, School of Chemical and Life Sciences, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India)

Chapter 2. Benzathiazole Analogs as Anticonvulsant and Anticancer Agents
(Ajayrajsinh R. Zala, Azazahemad Kureshi and Premlata Kumari, Department of Applied Chemistry, S. V. National Institute of Technology, Surat, Gujarat, India, and others)

Chapter 3. ESIPT Inspired Benzothiazole Fluorescent Molecules
(Vikas Patil, Bhavana V. Mohite, Satish V. Patil and Sharad Patil, University Institute of Chemical Technology, North Maharashtra University, Jalgaon, Maharashtra, India, and others)

Chapter 4. Benzothiazole: A Promising Scaffold for the Development of Anticancer Agents
(Shah Alam Khan, Asif Husain, Yaseen Moosa Al Lawatia and Saif Ahmad, College of Pharmacy, National University of Science and Technology, Muscat, Oman, and others)


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