Bacteriophages: Interaction, Diversity and Applications


: Microbiology Research Advances
BISAC: MED052000; SCI045000

The impact of viruses on the human population is inevitable. But not all viruses are deadly. There are good viruses that occupy our body and the environment. These bacteria-eating viruses are called bacteriophages. From birth to adulthood, bacteriophages have a consequential impact on human health by stabilizing the beneficial bacteria. Bacteriophages can arrest the bacterial machinery and kill them, which finds direct use in curing bacterial infections, known as phage therapy. In the future, phages, instead of antibiotics, will be used to treat bacterial diseases.

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Table of Contents

Sebastian Leptihn



Chapter 1. Introducing Bacteriophages
Sara Amiri Fahliyani
Department of Microbiology, Faculty of Biological Sciences, Falavarjan Branch, Islamic Azad University, Isfahan, Iran

Chapter 2. Understanding Bacteriophage-Host Interaction
VinodKumar C.S.¹and Suneeta Kalasuramath²
¹Department of Microbiology, Molecular Laboratory, S. S. Institute of Medical Sciences and Research Centre, Davanagere, Karnataka, India
²Department of Physiology, S. S. Institute of Medical Sciences and Research Centre, Davanagere, Karnataka, India

Chapter 3. Bacteriophage-Eukaryotic Host Interaction
Heba S. Abbas¹,²and Manal A. Nabil³
¹Microbiology Department, National Organization for Drug Control and Research (NODCAR), Recently, Egyptian Drug Authority, Giza, Egypt
²Microbiology Department, Faculty of Pharmacy, Misr University for Science and Technology, Giza, Egypt
³Department of Immunology and Allergy, Medical Research Institute, Alexandria University, Alexandria, Egypt

Chapter 4. Bacteriophage Genome and Replication
D. Saranya, S. Jeyaraman and N. H. Sathishkumar
Government Arts College, Udhagamandalam, India

Chapter 5. Structural and Morphological Diversity of Bacteriophages
Sangeeta Ahiwale¹ and Nusarat Shaikh²
¹Department of Microbiology, Mahatma Phule Mahavidyalaya, Pimpri, Pune, Maharashtra, India
²Department of Microbiology, Abeda Inamdar Senior college of Arts Science and Commerce, Azam Campus, Pune, Maharashtra, India

Chapter 6. Bacteriophages as Natural Predators
Anamika Rana, Ankita, Raj Shekhar Sharma, Shalini Kotiyal and Manjusha Tyagi
Department of Microbiology, School of Basic and Applied Science, SGRRU, Dehradun, Uttarakhand, India

Chapter 7.
Bacteriophages in Human Health
Fatma Abdelrahman¹, Maheswaran Easwaran²,³,4, Ritam Das5, Juhee Ahn³, Sheetal Patpatia6, Salsabil Makky¹, Hyun-Jin Shin4, Hussein Hablas7 and Ayman El-Shibiny¹
¹Center for Microbiology and Phage Therapy, Biomedical Sciences, Zewail City of Science and Technology, Giza, Egypt
²Department of Biomedical Engineering, Sethu Institute of Technology, Tamil Nadu, India
³College of Biomedical Science, Department of Medical Biomaterials Engineering, Kangwon National University, Chuncheon, Republic of Korea
⁴College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea
⁵Faculty of Biological Sciences, Friedrich Schiller University Jena, Germany
⁶Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
⁷Internal Medicine Department, El-Mataria Teaching Hospital, Cairo, Egypt

Chapter 8. Bacteriophages and Phage-Derived Endolysins as Antibacterials
Kandasamy Eniyan, Athira Sudarsanan and Nachimuthu Ramesh
Antibiotic resistance and Phage therapy Laboratory, School of Biosciences and Technology, Vellore Institute of Technology, Vellore, India

Chapter 9. Bacteriophages in Veterinary Medicine
Lahari Laddika¹, Shumaila Malik², Arfa Fayaz¹ and Richa Pachauri³
¹Veterinary Microbiology, ²Veterinary Bacteriology, ³Veterinary Virology, Biological standardization division, IVRI, Bareilly, UP

Chapter 10. Bacteriophages in the Treatment of Biofilms
Saroj and Urmi Bajpai
Department of Biomedical Science, Acharya Narendra Dev College, University of Delhi, New Delhi, India

Chapter 11.
Application of Bacteriophages in the Food Industry
Yukeswaran Loganathan and Moni Philip Jacob Kizhakedathil
Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam, Tamil Nadu, India

Chapter 12. Other Applications of Bacteriophages
Muhammad Saleem Iqbal Khan¹, Jinbiao Zhan¹, Zeeshan Umar², Kabeer Haneef³, Sana Ghaffar4 and Iqbal Alvi5
¹Department of Biochemistry, and Cancer Institute of the Second affiliated Hospital (Key Laboratory of Cancer Prevention and Intervention, China Ministry of Education), School of Medicine, Zhejiang University, Hangzhou, China
²Department of Pathogen Biology & Microbiology, Zhejiang University, School of Medicine, Hangzhou, China
³MOE Key Laboratory of Protein Science, School of Life Science, Institute for Immunology, Tsinghua University, Beijing, China
4Institute of Microbiology, University of Agriculture Faislabad, Pakistan
5Department of Microbiology, Hazara University, Mansehra, Pakistan

About the Editor

List of Contributors



Editor’s ORCID iD

Prasanth Manohar

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