Bacteriophages: Biology, Applications and Role in Health and Disease


Clark Denton (Editor)
Richard J. Crosby (Editor)

Series: Bacteriology Research Developments, Microbiology Research Advances
BISAC: SCI045000

Bacteriophages are obligate parasites that require bacterial hosts to replicate. Phages initiate infections by first attaching to the surface of bacteria and injecting their genomes into host cells. Virulent phages then hijack the host’s cellular machinery to direct the production of phage virons that burst from the cell leading to bacterial lysis. In this book, the authors discuss the biology, applications and role in health and disease of bacteriophages. Topics include the varied potential roles of bacteriophages in the production of food from animal sources; phage therapy, biocontrol and commercial microbiology; abortive infection as a killer bacteriophage resistance strategy; bacteriophages as biocontrol tools of pathogens in meat and dairy products; bacteriophages as probiotics and decontaminating agents for food products; use of bacteriophages as surrogate indicators of viruses in water; promoter sequences for bacteriophage RNA polymerases; the use of bacteriophages in bacterial food pathogen regulation; and the interaction between bacteriophage and its bacterial host receptor, LamB. (Imprint: Nova Biomedical )


Table of Contents

Table of Contents


Bacteriophages from Farm to Fork: The Varied and Potential Roles of Bacteriophages in the Production of Food from Animal Sources
(J. Owens, K. R. Hodgson, Faculty of Veterinary Science, The University of Melbourne, Parkville, Victoria, Australia, and others)

The Use of Phage: Therapy, Biocontrol and Commercial Microbiology
(Roberto S. Dias, Monique R. Eller, Rafael L. Salgado, Cynthia C. da Silva, Sérgio O. De Paula, Laboratory of Molecular Immunovirology, Department of General Biology, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil)

Abortive Infection: A Killer Bacteriophage Resistance Strategy of Last Resort
(Chidiebere Akusobi, Feng Rao, Francesca L. Short, George P. C. Salmond, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom)

Bacteriophages as Biocontrol Tools of Pathogens in Meat and Dairy Products
(David Tomat, Diego Mercanti, Claudia Balague, Andrea Quiberoni, Cátedra de Bacteriología, Área Microbiología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha, Rosario, Argentina, and others)

Bacteriophages as Probiotics and Decontaminating Agents for Food Products
(Andrei V. Aleshkin, Nikolay V. Volozhantsev, Edward A. Svetoch, Stanislav S. Afanas’ev, Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Russian Federation, and others)

Use of Bacteriophages as Surrogate Indicators of Viruses in Water
(Fatma Hmaied, Sihem Jebri, Laboratoire de Microbiologie et Biologie Moléculaire, CNSTN, Pôle Technologique, Sidi Thabet, Tunisie)

Strategies for the Analysis and Engineering of Promoter Sequences for Bacteriophage RNA Polymerases
(Shoji Ohuchi, Department of Medical Genome Science, University of Tokyo, Kashiwanoha, Kashiwa-shi, Japan)

The Use of Bacteriophages in Bacterial Food Pathogen Regulation
(Rogeria C.C. Almeida, Lívia P.R. Rossi, Paulo F. Almeida, Universidade Federal da Bahia, Departamento de Ciência dos Alimentos da Escola de Nutrição, Salvador, BA, Brazil, and others)

The Interaction between Bacteriophage λ and its Bacterial Host Receptor, LamB
(Sujoy Chatterjee, Eli Rothenberg, Department of Biochemistry and Molecular Pharmacology, NYU Medical School, NY, USA)



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