Bacteriophages and Biofilms: Ecology, Phage Therapy, Plaques

Stephen T. Abedon
The Ohio State University, Mansfield, OH , USA

Series: Bacteriology Research Developments, Biotechnology in Agriculture, Industry and Medicine
BISAC: SCI006000

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Bacteriophages (phages) are the viruses of bacteria and biofilms that represent a frequent niche for bacteria, where they are embedded in extensive extracellular polymeric substances (EPS) and can be structured into complex microcolonies. As a consequence of the resulting spatial structure and heterogeneity, phage-bacterial interactions within biofilms can be more complicated than those between phages and planktonic bacteria. This book presents and discusses research which provides a better understanding of the biology of phages interacting with biofilms. (Imprint: Novinka)

Introduction

1. Microbiology, Bacteriophages, Biofilms

2. Viewing Phages from a Phage Perspective

3. Phage-Biofilm Interactions—Phage Perspective

4. Phage-Biofilm Interactions—Bacterium Perspective

5. Phage Therapy

6. Phages as Anti-Biofilm Agents

7. Phage Therapy Lessons Gleaned

8. Phage Plaques as Models of Biofilm Exploitation

9. Phage Penetration into Bacterial Microcolonies

10. Conclusion

Appendices:

1. Poisson distribution

2. Multiplicity of infection

3. Killing titer

4. Bacteria reduction times

5. Phage plaques

Index

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