Bacteriophages and Biofilms: Ecology, Phage Therapy, Plaques

Stephen T. Abedon
The Ohio State University, Mansfield, OH , USA

Series: Bacteriology Research Developments, Biotechnology in Agriculture, Industry and Medicine
BISAC: SCI006000




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Bacteriophages (phages) are the viruses of bacteria and biofilms that represent a frequent niche for bacteria, where they are embedded in extensive extracellular polymeric substances (EPS) and can be structured into complex microcolonies. As a consequence of the resulting spatial structure and heterogeneity, phage-bacterial interactions within biofilms can be more complicated than those between phages and planktonic bacteria. This book presents and discusses research which provides a better understanding of the biology of phages interacting with biofilms. (Imprint: Novinka)


1. Microbiology, Bacteriophages, Biofilms

2. Viewing Phages from a Phage Perspective

3. Phage-Biofilm Interactions—Phage Perspective

4. Phage-Biofilm Interactions—Bacterium Perspective

5. Phage Therapy

6. Phages as Anti-Biofilm Agents

7. Phage Therapy Lessons Gleaned

8. Phage Plaques as Models of Biofilm Exploitation

9. Phage Penetration into Bacterial Microcolonies

10. Conclusion


1. Poisson distribution

2. Multiplicity of infection

3. Killing titer

4. Bacteria reduction times

5. Phage plaques


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