Astrocytes: Structure, Functions and Role in Disease

Oscar González-Pérez (Editor)
Laboratory of Neuroscience, School of Psychology, University of Colima, Colima, Mexico

Series: Neuroscience Research Progress, Neurology – Laboratory and Clinical Research Developments
BISAC: SCI089000

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Volume 10

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Volume 2

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Astrocytes are the main glial cell type in the central nervous system. These cells were originally regarded as supportive cells of the brain, but increasing evidence indicates they play fundamental roles in many brain functions, such as: neurotransmitters uptake, energy homoeostasis, neurogenesis, myelination, immunomodulation, neurotrophic factor releasing and blood-brain-barrier maintenance. This book summarizes the latest discoveries, from basic to clinical science, regarding the main roles of astrocytes under physiological and pathological circumstances. To ensure that most of readers obtain clear and complete information, all chapters have been written in plain language by worldwide-recognized experts in their respective fields. (Imprint: Nova Biomedical )

Preface

Chapter 1. Role of Drug-metabolizing Enzymes in Astroglial Function
(Amruthesh C. Shivachar, Dakota Jackson and Shere`Paris, Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX USA)

Chapter 2. Astrocytic Potassium Channels in CNS Disorders
(Miroslava Anderova and Helena Pivonkova, Department of Cellular Neurophysiology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska Prague 4- Czech Republic)

Chapter 3. The Phosphoinositides Signal Transduction Pathway in Astrocytes
(Vincenza Rita Lo Vasco, Department Organi di Senso, Policlinico Umberto I Faculty of Medicine and Odontoiatry, Sapienza University of Rome. Viale del Policlinico, Rome, Italy)

Chapter 4. Astrocytes as neural stem cells in the adult brain
(Oscar Gonzalez-Perez, Laboratory of Neuroscience. School of Psychology. University of Colima. Colima, Col., Mexico, Departamento de Neurociencias, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara. Guadalajara, Jal. México)

Chapter 5. Ultrastructural characteristics of astrocytic neural stem cells in the adult brain
(Irene Sanchez-Vera, Arantxa Cebrian-Silla, MªSalome Sirerol-Piquer, Jose Manuel Garcia-Verdugo, Laboratorio de Morfologia Celular, Centro de Investigacion Principe Felipe, CIBERNED. Avda. Autopista del Saler nº16, CP: Valencia, Spain and others)

Chapter 6. Aging, Environmental Enrichment, Object Recognition and Astrocyte Plasticity in Dentate Gyrus
(Daniel Guerreiro Diniz, César Augusto Raiol Foro, Marcia Consentino Kronka Sosthenes, João Bento- Torres, Pedro Fernando da Costa Vasconcelos, Cristovam Wanderley and Picanço-Diniz, Universidade Federal do Pará, Instituto de Ciências Biológicas, Laboratório de Investigações em Neurodegeneração e Infecção – Hospital Universitário João de Barros Barreto, Rua Mundurucus, Guamá, CEP Belém, Pará, Brazil and others)

Chapter 7. Role of Astrocytes in Viral Infections
(Cecilia Bender, Jesica Frik and Ricardo M. Gomez, Graduate School for Life and Health Sciences, University of Verona, Italy and others)
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Chapter 8. Astrocyte dysfunction in megalencephalic leukoencephalopathy with Subcortical Cysts
(Raul Estevez, Department Physiological Sciences II, School of Medicine, University of Barcelona, Barcelona, Spain and others)

Index

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