Astrocytes and Their Role in Health and Disease

$82.00 – $123.00

Tomaz Velnar, MD, PhD – Professor, Department of neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia
Lidija Gradisnik, PhD – Researcher, Institute of biomedical sciences, Medical Faculty Maribor, Maribor, Slovenia

Series: New Developments in Medical Research
BISAC: MED009000; MED106000
DOI: https://doi.org/10.52305/WJDN2747

Astrocytes are some of the key cells in the central nervous system with complex, specific and important roles. They are involved in many important functions under both physiological and pathological conditions. This book brings a theoretical overview on astrocytes, their functions, roles and experimental practice. Chapters 1 and 2 discuss the basic astrocyte functions and their connections with other central nervous system cells. Chapter 3 focuses on the blood-brain barrier, Chapter 4 summarises surgical methods for tissue collection, Chapter 5 deals with the laboratory isolation procedure, Chapter 6 describes the sources of astrocyte isolation and troubleshooting during this procedure and Chapter 7 explores the importance of biomaterial research in astrocyte cell models.

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Table of Contents

Preface

Chapter 1. Astrocytes – An Overview of Their Functions
Lidija Gradisnik1, Borut Prestor2 and Tomaz Velnar2
1Institute of Biomedical Sciences, Medical Faculty Maribor, Maribor, Slovenia
2Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia

Chapter 2. The Astrocytes and Astroglia Morphology and Their Biological Properties
Bratko Filipic1, Lidija Gradisnik2 and Hrvoje Mazija1
1CIETO (Croatian Institute for Experimental and Translational Oncology), Zagreb, Croatia
2Institute of Biomedical Sciences, Medical Faculty Maribor, Maribor, Slovenia

Chapter 3. The Role of Astrocytes in Human Artificial Blood-Brain Barrier Models
Tanja Zidaric1, Tomaz Velnar2 and Lidija Gradisnik1
1Institute of Biomedical Sciences, Medical Faculty Maribor, Maribor, Slovenia
2Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia

Chapter 4. The Clinical Viewpoints of Neurosurgical Methods in Brain Tissue Sampling for In Vitro Cell Isolation
Lidija Gradisnik1, Roman Bosnjak2, Tomaz Velnar2 and Borut Prestor2
1Institute of Biomedical Sciences, Medical Faculty Maribor, Maribor, Slovenia
2Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia

Chapter 5. An Improved Protocol for Adult Human Astrocyte Isolation and Culture Establishment
Lidija Gradisnik1, Uros Maver1 and Tomaz Velnar2
1Institute of Biomedical Sciences, Medical Faculty Maribor, Maribor, Slovenia
2Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia

Chapter 6. The Need for Astrocyte Cell Cultures – Troubleshooting
Lidija Gradisnik1, Tomaz Velnar2 and Roman Bosnjak2
1Institute of Biomedical Sciences, Medical Faculty Maribor, Maribor, Slovenia
2Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia

Chapter 7. Bio-Polymers for Astrocyte Cell Models in In Vitro Research
Lidija Gradisnik1, Tina Maver1 and Tomaz Velnar2
1Institute of Biomedical Sciences, Medical Faculty Maribor, Maribor, Slovenia
2Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia

Index

Editor’s ORCID iD

Tomaz Velnar  – https://orcid.org/0000-0002-6283-4348
Lidija Gradisnik – https://orcid.org/0000-0003-3492-0297

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