Arteriovenous Malformations: A Comprehensive Guide to Natural History, Diagnosis and Management


Series: Congenital Disorders – Laboratory and Clinical Research
BISAC: MED022000

Arteriovenous malformations (AVM) represent some of the most complex and challenging pathologies for the modern physician to properly diagnose and manage. In this comprehensive guide, we detail the natural history, diagnosis and management of AVMs. The first eight chapters are dedicated to brain AVMs. Chapter 1 describes the natural history of brain AVMs, the understanding of which is crucial to deciphering the relative risks and benefits of AVM treatment. Chapter 2 focuses on the surgical treatment of brain AVMs. Chapters 3 and 4 delineate the role of endovascular embolization in the management of brain AVMs. Chapter 5 analyzes the outcomes of stereotactic radiosurgery for Spetzler-Martin grade III AVMs, which are the most heterogeneous subgroup of AVMs. Chapter 6 describes the role of stereotactic radiosurgery for large brain AVMs, which are notoriously difficult to safely and effectively treat by any means. Chapter 7 focuses on heavily charged particle beam radiosurgery for brain AVMs. Chapter 8 puts it all together by analyzing the relationships and interactions among the different treatment modalities for brain AVMs; when utilized synergistically, the morbidity of each therapy is minimized while its maximum benefit is extracted. The last two chapters are dedicated to Osler-Weber-Rendu syndrome, also known as hereditary hemorrhagic telangiectasia (HHT). Chapter 9 describes the genetics, pathogenesis, and management of HHT, with a focus on the diagnosis of pulmonary AVMs. Chapter 10 evaluates the role of endovascular intervention in the treatment of pulmonary AVMs.
(Imprint: Nova Biomedical)

Table of Contents

Table of Contents


1. The Natural History of Cerebral Arteriovenous Malformations
(Bradley A. Gross, Department of Neurological Surgery, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America)

2. Surgical Management of Cerebral Arteriovenous Malformations: Indications, Preoperative Evaluation, and Outcomes
(Colin J. Przybylowski, Dale Ding, Robert M. Starke, R. Webster Crowley, Kenneth C. Liu, Department of Neurosurgery, University of Virginia, Charlottesville, Virginia, United States of America)

3. Embolization of Arteriovenous Malformations: Products and Protocols
(Peter S. Amenta, Derrick Umansky, Ricky Medel, Aaron S. Dumont, Department of Neurosurgery, Tulane University, New Orleans, Louisiana, United States of America)

4. Endovascular Management of Cerebral Arteriovenous Malformations: Embolic Agents, Outcomes, and Technological Advances
(Colin J. Przybylowski, Dale Ding, Robert M. Starke, Kenneth C. Liu, Webster Crowley, Department of Neurosurgery, University of Virginia, Charlottesville, Virginia, United States of America)

5. Stereotactic Radiosurgery for Spetzler-Martin Grade III Arteriovenous Malformations
(Hideyuki Kano, L. Dade Lunsford, Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America)

6. Stereotactic Radiosurgery for Large Cerebral Arteriovenous Malformations
(Cheng-Chia Lee, Huai-Che Yang, Wen-Yuh Chung, David Hung-Chi Pan, Jason P. Sheehan, Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan)

7. Heavy Charged Particle Beam Radiosurgery for Arteriovenous Malformations of the Brain
(Frederik J. Vernimmen, Sandra M. Sinske, Department of Radiation Oncology, Cork University Hospital, Cork, Ireland)

8. Multimodality Treatment of Arteriovenous Malformations
(Arundhati Biswas, David J. Altschul, Department of Neurological Surgery, Montefiore Medical Center, Bronx, New York, United States of America)

9. Hereditary Hemorrhagic Telangiectasia: Genetics, Pathogenesis, Diagnosis of Pulmonary Arteriovenous Malformations, and Clinical Management
(V.M.M. Vorselaars, S. Velthius, R.J. Snijder, C.J.J. Westermann, J.A. Vos, J.J. Mager, M.C. Post, Department of Cardiology, St. Antonius Hospital, CM Nieuwegein, The Netherlands)

10. Endovascular Treatment of Pulmonary Arteriovenous Fistulas in Osler-Weber-Rendu Syndrome
(Naiem Nassiri, Robert Rosen, Jones Thomas, Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States of America)


This book is primarily written for physicians who treat patients harboring AVMs. Professionals who may find this book useful include neurosurgeons, neurologists, interventional neuroradiologists, and radiation oncologists. Industries this book may appeal to include companies which design surgical, radiosurgical, and endovascular devices which treat AVM patients.

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