Apigenin and Naringenin: Natural Sources, Pharmacology and Role in Cancer Prevention


Nilus M. Stacks (Editor)

Series: Biochemistry Research Trends
BISAC: MED071000

Apigenin is one of the most bioactive naturally occurring flavonoids, found in fruits, plant-derived beverages, vegetables, wheat sprouts, and some seasonings. It has been found to possess anti-oxidant, anti-inflammatory, and anti-cancer properties. Naringenin is one of the most studied flavonoids abundant in citrus plants. Naringenin and their derivatives are known to exhibit strong anti-oxidant potential along with plenty of protective effects for the improvement of human health. This book discusses the natural sources, pharmacology and role in cancer prevention of the flavonoids, apigenin and naringenin. (Imprint: Nova)

Table of Contents

Table of Contents


Chapter 1 – Drug Delivery Approaches for Apigenin: A Review (pp. 1-20)
Zsófia Edit Pápay, Emese Balogh, Mohammed Gulrez Zariwala, Satyanarayana Somavarapu and István Antal (Department of Pharmaceutics, Semmelweis University, Budapest, Hungary, and others)

Chapter 2 – Antimetastatic Potential of Apigenin (pp. 21-30)
Daniele Maggioni, PhD (University of Milan-Bicocca, Department of Surgery and Translational Medicine, Milan, Italy)

Chapter 3 – Nanotechnology Based Apigenin Drug Delivery Systems (pp. 31-40)
Ranjita Shegokar (Freie Universität Berlin, Institute of Pharmacy, Department Pharmaceutics, Biopharmaceutics & NutriCosmetics, Kelchstraße, Berlin, Germany)

Chapter 4 – Update on Properties of Apigenin Related to Inflammatory Process (pp. 41-52)
Gorzalczany Susana (Pharmacology Department, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina)

Chapter 5 – Inhibitory Effects of Apigenin on Mammalian DNA Polymerase and Proliferation of Human Cancer Cells (pp. 53-74)
Yoshiyuki Mizushina, Kazuaki Shiomi, Takefumi Onodera and Isoko Kuriyama (Laboratory of Food & Nutritional Sciences, Faculty of Nutrition, Kobe Gakuin University, Nishi-ku, Kobe, Hyogo, Japan, and others)

Chapter 6 – Chemoprevention by Apigenin through Induction of Apoptosis and Autophagy (pp. 75-106)
Bokyung Sung and Nam Deuk Kim (Department of Pharmacy, Molecular Inflammation Research Center for Aging Intervention, Pusan National University, Republic of Korea)

Chapter 7 – Role of Apigenin in Cancer Prevention (pp. 107-136)
Rit Bahadur Gurung, Ramesh Prasad Pandey and Jae Kyung Sohng (Institute of Biomolecule Reconstruction (iBR), Department of Pharmaceutical Engineering, Sun Moon University, Kalsan-ri, Tangjeong-myeon, Asan-si, Chungnam, Republic of Korea)

Chapter 8 – Naringenin Regulates the Intestinal Tight Junction Barrier and Inflammation (pp. 137-150)
Takuya Suzuki (Department of Biofunctional Science and Technology, Graduate School of Biosphere Science, Hiroshima University, Japan)

Chapter 9 – Dietary Sources, Bioavailability and Biological Activities of Naringenin and Its Derivative (pp. 151-172)
Ramesh Prasad Pandey, Rit Bahadur Gurung and Jae Kyung Sohng (Department of Pharmaceutical Engineering, Institute of Biomolecule Reconstruction, Sun Moon University, Kalsan-ri, Tangjeong-myeon, Asan-si, Chungnam, Republic of Korea)


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