Antimicrobial Peptides: Functions, Mechanisms of Action and Role in Health and Disease

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Paresh Chandra Ray, PhD (Editor) – Professor, Department of Chemistry, Physics and Atmospheric Sciences, Jackson State University, Mississippi, USA

Series: Microbiology Research Advances
BISAC: MED052000
DOI: https://doi.org/10.52305/CQGC8374

The increasing prevalence of antibiotic-resistant bacteria, known as superbugs, has threatened the field of infectious disease medicine over most of the past century. Antimicrobial peptides, a crucial part of innate immunity that exists in most living organisms, have become a central pillar for the next generation of medical challenges for infectious diseases, cancer, and other health problems. The development of new antimicrobial peptides to tackle ongoing superbug infections, cancer and other diseases is a fast-growing research area for chemistry, medical physics, biological science, food and agricultural science and different disciplines of medicine. This volume discusses the basic science behind potential pharmacological agents, which is necessary to understand how these peptides can be used in our daily lives. The book provides a foundation for a wide variety of antimicrobial peptide-based therapeutic approaches, which is invaluable for established scientists, junior researchers, and students involved in basic science, material science, the medical field and different disciplines of engineering. It contains nine chapters written by world leaders in this area, covering basic science and possible therapeutic applications with immense societal implications. Antimicrobial peptides are an exciting new therapeutic agent with promising applications for a wide variety of illnesses.

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Table of Contents

Preface

Chapter 1. Antimicrobial Peptides: Potential as Alternative or Complementary Treatments for Infectious Agents
(Maryam Ghahri, Nadin Shagaghi, Enzo A Palombo and Mrinal Bhave – Department of Chemistry and Biotechnology, Swinburne University of Technology, Hawthorn, Victoria, Australia)

Chapter 2. Multiple Antimicrobial Peptides Conjugated Biochar Based Nanoarchitecture for Combating Superbugs
(Ye Gao, Shamily Patibandla, Avijit Pramanik and Paresh Chandra Ray – Department of Chemistry, Physics and Atmospheric Sciences, Jackson State University, Jackson, MS, US)

Chapter 3. Versatile Biological Properties of Antimicrobial Peptides in Health and Disease
(Salma Begum – National Institutes of Health, Bethesda, MD, USA)

Chapter 4. Uperin Antimicrobial Peptides: Structures, Activity, and Amyloid Fibril Formation
(Verity Baltutis, Antonio N. Calabrese, John A. Carver and Lisandra L. Martin – School of Chemistry, Monash University, Clayton, Victoria, Australia, et al.)

Chapter 5. The Potential of Antimicrobial Peptides in Breast Cancer Treatment
(Bhanu Priya Viraka Nellore and Rajashekhar Kanchanapally – Department of Natural Sciences and Environmental Health, Mississippi Valley State University, Itta Bena, Mississippi, US, et al.)

Chapter 6. Peptide Conjugated Graphene Based Smart Materials for Antibacterial and Cancer Therapy
(Avijit Pramanik, Shamily Patibandla, Ye Gao and Paresh Chandra Ray – Department of Chemistry, Physics and Atmospheric Sciences, Jackson State University, Jackson, Mississippi, US)

Chapter 7. Antimicrobial Peptide-Modified Nanomaterials for Detection and Extermination of Bacteria
(Rajashekhar Kanchanapally, Oluwapelumi P. Shodubi, Morolake R. Okanlawon and Bhanu Priya Viraka Nellore – Department of Chemistry and Physics, Natural Science Division, Tougaloo College, Tougaloo, Mississippi, US, et al.)

Chapter 8. Antimicrobial Peptide Conjugated Nanostructures for Biosensing and Destruction of Antimicrobial Resistant Microbes
(Santanu Banerjee – Department of Physics, Tougaloo College, Tougaloo, Mississippi, US)

Chapter 9. Antimicrobial Peptide Attached Gold Nanoparticle Based Theranostic Nanoplatform
(Shamily Patibandla, Avijit Pramanik, Ye Gao and Paresh Chandra Ray – Department of Chemistry, Physics and Atmospheric Sciences, Jackson State University, Jackson, Mississippi, US)

Index

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