Antihypertensive Drugs: Pharmacology, Medical Uses and Potential Side Effects

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Scott Caldwell (Editor)

Series: Pharmacology – Research, Safety Testing and Regulation
BISAC: MED071000

Pulmonary arterial hypertension (PAH) is a progressive, fatal syndrome characterized by increased pulmonary vascular resistance that leads to right-ventricular hypertrophy and heart failure, eventually leading to premature death. Arterial hypertension is one of the most important preventable contributors to disease and death, and is commonly treated with antihypertensive drugs combined with appropriate changes in life-style.

Most of the drugs used in the hypertension treatment are administered orally in solid form and therefore they can crystallize in different crystalline forms. There are many classes of antihypertensive drugs which decrease blood pressure by different mechanisms. This book discusses the pharmacology, medical uses and potential side effects of antihypertensive drugs. (Imprint: Nova Biomedical)

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Table of Contents

Preface

Antihypertensive Drugs as Chiral Agents
(R. Čižmáriková, J. Valentová, A. Némethy, I. Pechová, Department of Chemical theory of drugs, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic)

Evaluation of Genotoxic Effects of Antihypertensive Drugs: Angiotensin II Receptor Blockers
(Iratxe Huerta, Maitane Barasoain, Mercedes Télez, Eduardo Ortiz-Lastra, Javier González, Mikel Longa, Javier Muga, Gorka Barrenetxea, Begoña Criado, Isabel Arrieta, Department of Genetics,Physical Anthropology and Animal physiology, Faculty of Science and Technology, University of the Basque Country, Bilbao, Spain, and others)

Effects of the Polymorphism in Antihypertensive Drugs
(Márcia C. de Souza, Weberton R. do Carmo, Chris H. J. Franco, Luan F. Diniz and Renata Diniz, Grupo de Cristalografia de Pequenas Moléculas (GCPMOL), Departamento de Química, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil)

Management of the Black Hypertensive Patient in a Resource Limited Setting
(Ifeoma I. Ulasi, Chinwuba K Ijoma, Benedict C Anisiuba, Ngozi A Ifebunandu, Uchenna C Ijoma, Dept of Medicine, College of Medicine, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Nigeria, and others)

Index

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