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A. Falco, M. Ortega-Villaizan, J.M. Coll and A. Estepa
Miguel Hernández University, Elche, Spain, and others
Series: Immunology and Immune System Disorders
BISAC: MED044000
Among the 5 structural proteins of the salmonid rhabdovirus viral haemorrhagic septicaemia virus (VHSV), the glycoprotein G (gpG) is a unique immunogenic (immune response) and antigenic (antibody) inducer. While recombinant gpG proteins had limited success as vaccines, their corresponding gpG DNA have been highly protective in different fish species (most probably because that is the best way to maintain their epitopes, disulphide bonds and glycosilation). (Imprint: Novinka)
Table of Contents
Summary
Importance of Rhabdoviral Diseases in Farmed Fish
Viral Haemorrhagic Septicemia Virus (VHSV)
The Structure-Function Relationships in the Glycoprotein G of VHSV (gpGVHSV)
The Importance of the gpGVHSV in Vaccination against VHSV
Early gpGVHSV Immunogenicity: Activation of the Interferon (IFN) System
Long-Term gpG Immunogenicity: Induction of T Cellular Responses
Long-Term gpGVHSV Antigenicity: Antibody Responses
References
Index
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