Angiogenesis: Insights from a Systematic Overview


Gaetano Santulli, MD, PhD (Editor)
Columbia University Medical Center, College of Physicians & Surgeons, Columbia University, New York, NY, USA

Series: Cell Biology Research Progress
BISAC: SCI017000

This book provides an overview of the scientific methods used to search, analyse, appraise and synthesize studies on angiogenesis. It is intended to serve as a comprehensive piece of literature that encompasses all aspects from the molecular features of angiogenesis to the clinical value and potential pitfalls of angiogenic-based therapies. The primary motion to write this book is to provide an overview of the current status of the research in this field, with a focus on both tumoral and non-tumoral disease. Effects of various anti-angiogenic and pro-angiogenic molecules are also addressed in detail.

This book comes at an important time in the development of so-called “translational medicine”. Its purpose is to explain all the molecular bases underlying the angiogenic process and apply them to the clinical world. Reviewed and addressed are the basic concepts and importance of new drugs in clinical trials to inhibit or promote angiogenesis. This book may be considered as a scholarly reference work for libraries and researchers across the world and as a supplementary text for courses in medicine, physiology, biochemistry, molecular and cellular biology. It is expected that readers, both basic researchers and clinicians, will gain a good understanding of the essential value of angiogenesis in health and disease. (Imprint: Nova Biomedical )


Table of Contents

Table of Contents

Chapter 1. Angiogenesis: Something Old, Something New
(Evangeli Lampri and Elli Ioachim, Cancer Biobank Center of the University of Ioannina, Greece and others)

Chapter 2. A Historical Appraisal of Angiogenesis Assays since Judah Folkman and Before…
(Anca Maria Cimpean, Domenico Ribatti and Marius Raica, Department of Histology, Angiogenesis Research Center, “Victor Babeþ” University of Medicine and Pharmacy, Timisoara, Romania and others)

Chapter 3. Angiogenesis and Pulmonary Hypertension
(Daling Zhu, Cui Ma and Jing Li, Biopharmaceutical Key Laboratory of Heilongjiang Province, College of Pharmacy, Harbin Medical University
Heilongjiang, PR China)

Chapter 4. Stem Cells and Angiogenesis in Skeletal Muscle Regeneration and Disease
(Carlos Hermano da Justa Pinheiro, Lucas Guimarães Ferreira and Marco Aurélio Salomão Fortes, Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil, and others)

Chapter 5. Angiogenesis in Peripheral Artery Disease: An Emerging Therapy Targeting Skeletal Muscle
(Brian D. Duscha, Jennifer L. Robbins, Christopher D. Kontos, William E. Kraus and Brian H. Annex, Duke University Medical Center, Division of Cardiology, Durham, NC, USA, and others)

Chapter 6. Angiogenesis in Thalassemia
(Seref Olgar and Duran Canatan, Pediatric Cardiologist, Sutcu Imam University, Department of Pediatric Cardiology, Kahramanmaras, Turkey, and others)

Chapter 7. Fibroblasts and Endothelial Cells: The Basic Angiogenic Unit
(François Berthod, Centre LOEX de l’Université Laval, Centre de recherche du CHU de Québec, and Département de Chirurgie, Faculté de Médecine, Université Laval, Québec, Canada)
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Chapter 8. Regulating Functions of Angiogenesis in Prevention and Therapy of Gastric Ulcers
(Snehasikta Swarnakar, Krishnendu Ganguly and Sumit Paul, Drug Development Diagnostics and Biotechnology Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India, and others)

Chapter 9. The Role of Angiogenesis in Renal Allograft
(B. Handan Özdemir, Department of Pathology, Baskent University, Ankara, Turkey)

Chapter 10. Angiogenesis and Lymphangiogenesis as Molecular Therapeutic Targets in Human Pterygium And Its Recurrences
(Anca Maria Cîmpean, Mihai Poenaru Sava and Marius Raica, Department of Histology, “Victor Babeþ” University of Medicine and Pharmacy, Timisoara, Romania, and others)

Chapter 11. The Role of Heparin Mimetic Peptide Nanofibers in Angiogenesis Process
(Rashad Mammadov, Elif Duman, Mustafa O. Guler and Ayse B. Tekinay, Institute of Materials Science and Nanotechnology, National Nanotechnology Research Center (UNAM), Bilkent University, Ankara, Turkey)

Chapter 12. Mast Cells and Angiogenesis in Tumoral and Non-Tumoral Disease
(Azize Yasemin Goksu Erol and Fatma Aktepe, Department of Histology & Embryology, Faculty of Medicine, Afyon Kocatepe University, Afyon, Turkey, and others)

Chapter 13. Angiogenesis in Tumor Microenvironment: Potential Approaches in Cancer Therapy
(Mehmet Sahin, Emel Sahin and Sadi Koksoy, Akdeniz University, Antalya, Turkey)

Chapter 14. Angiogenesis in Breast Neoplasia
(Evangeli Lampri and Elli Ioachim, Cancer Biobank Center, University of Ioannina, Greece, and others)

Chapter 15. Targeting VEGF-Mediated Tumor Angiogenesis in Neuroblastoma
(Danielle Hsu and Eugene S. Kim, Division of Pediatric Surgery,
Michael E. DeBakey Department of Surgery, Baylor College of Medicine
Houston, TX, USA)

Chapter 16. Molecular Pathways of Angiogenesis in Cervical Cancer
(Oana Tudoran, Ovidiu Balacescu and Ioana Berindan-Neagoe, Department of Functional Genomics and Experimental Pathology, I. Chiricuta Cancer Institute, Cluj-Napoca, Romania)


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