Table of Contents
Preface
Chapter 1. Introduction: Structure and Function
(Anupam Dhasmana, Sudhir Kotnala, Murali M. Yallapu, Subhash C. Chauhan and Meena Jaggi – Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX, US, et al.)
Chapter 2. Relative Distribution of P-Glycoprotein (P-gp) and its Pharmacological Relevance
(Nishant S. Kulkarni, Snehal K. Shukla and Vivek Gupta – Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences,St. John’s University, Queens, NY, US)
Chapter 3. P-gp Pathophysiology: Post-Translational Modification and Affecting Signaling Cascades
(Sree-Pooja Varahachalam, Jaspreet Kaur, Minitha Jacob, Behnaz Lahooti, Tanya Chhibber, Alexis Hyman, Abhijeet Joshi and Rahul Dev Jayant – Department of Pharmaceutical Sciences, JH School of Pharmacy, Texas Tech University Health Science Center, Amarillo, TX, USA, et al.)
Chapter 4. Mechanistic Comprehension towards the Role of P-Glycoprotein in Limiting the Pharmacokinetic and Pharmacological Efficacy of Drugs
(Swati Chaturvedi, Nazneen Sultana, Mamunur Rashid, Divya Chauhan, Zaiba Naseem, Ravindra V. Alluri and Wahajuddin – Pharmaceutics and Pharmacokinetics Division, CSIR- Central Drug Research Institute, Lucknow, India, et al.)
Chapter 5. P-Glycoprotein, a Biological and Medicinal Chemistry/Radiochemistry Point of View
(Carmen Abate, Nicola Antonio Colabufo and Marialessandra Contino – Dipartimento di Farmacia-Scienze del Farmaco, UniversitĂ degli Studi di Bari, Bari, Italy)
Chapter 6. P-Glycoprotein: A New Insight in the Field of Neurogenesis with a Different Perspective
(Virendra Tiwari, Akanksha Mishra, Sonu Singh and Shubha Shukla – Neuroscience and Ageing Biology Division, CSIR- Central Drug Research Institute, (U.P.), India, et al.)
Chapter 7. Formulation Strategies to Bypass P-Glycoprotein Mediated Drug Efflux
(Viral Shah and Manish Nivsarkar – Dept. of Pharmaceutics, B. V. Patel, Pharmaceutical Education and Research Centre, Ahmedabad, Gujarat, India, et al.)
Chapter 8 Marine Sources Potentiate to Inhibit P-Glycoprotein for the Management of Cancers and Multidrug Resistance
(Varish Ahmad, Qazi Mohammad Sajid Jamal, Sohail Akhtar, Aftab Ahmad, Zaiba Naseem, Mohammed F. Abuzinadah and Shahid Karim – Health Information Technology Department, Faculty of Applied Studies, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, et al.)
Chapter 9. P-Glycoprotein and Its Association in Neurodegenerative Disorders
(Himani Panwar, Anushruti Ashok, Swati Chaturvedi, Ranjay Kumar Chaudhary, Arti Thakur and Sadaf Jahan – Gurukul Kangri Vishwavidyalaya, Haridwar, Uttarakhand, India, et al.)
Chapter 10. P-Glycoprotein Polymorphism: Genetic and Epigenetic Changes
(Tarique Mahmood Ansari, Mohammad Haris Siddiqui, Malik Mobeen, Farogh Ahsan and Arshiya Shamim – Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, et al.)
Chapter 11. Quantification and Analysis of P-Glycoprotein: In Vitro, In Situ, and In Vivo Models
(Deepak S. Chauhan, Meena Jaggi, Subhash C. Chauhan and Murali M. Yallapu – Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX, US, South Texas Center of Excellence in Cancer Research, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX, US)
Chapter 12. Recent Advancements and Future Perspectives
(Nazneen Sultana, Swati Chaturvedi, Divya Chauhan and Wahajuddin – Pharmaceutics and Pharmacokinetics Division, CSIR – Central Drug Research Institute, Lucknow, Uttar Pradesh, India, et al.)
Index