An Essential Guide to Rutin

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Joachim E. Bach (Editor)

Series: Biochemistry Research Trends
BISAC: SCI007000

Rutin (3`,4`, 5,7-tetrahydroxyflavone-3-D-rutinoside), known as vitamin P, is one of the biologically active flavonoids widely present in plants. In living organisms, rutin binds Fe2+ and prevents the reaction of those ions with hydrogen peroxide.

In one study, the authors set out to determine the effects of rutin on protective capacity (xenobiotic-metabolizing enzymes and antioxidant status) in intact rats and under oxidative stress. The results showed that in healthy, intact rats and under oxidative stress, rutin can activate the enzyme systems responsible for the protective capacity of the organism.

In closing, a review study is presented regarding simple and sensitive enzymatic electrochemical biosensors developed to detect rutin. This study focused on the construction of chemical sensors using metal nanoparticles and biosensors with carbon paste electrodes modified with different materials used for enzyme immobilization, such as: metallic nanoparticles, carbon nanotubes, ionic liquids, chitosan and cyclodextrin.
(Imprint: Novinka)

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Table of Contents

Preface

Chapter 1. Rutin: Study of Electrochemical and Antioxidant Properties
(Martina Medvidović-Kosanović, Silvija Šafranko, Anamarija Stanković, Stela Jokić and Marija Jozanović, Department of Chemistry, J. J. Strossmayer University of Osijek, Osijek, Croatia, and others)

Chapter 2. Effects of Rutin on Protective Capacity in Intact Rats and under Oxidative Stress
(Ilya V. Aksenov, PhD, Nikita V. Trusov, MD, Anastasia V. Balakina, MD, Ludmila I. Avrenyeva, PhD,
Galina V. Guseva, PhD, Lidia V. Kravchenko, PhD, and Victor A. Tutelyan, PhD, Federal Research Centre of Nutrition and Biotechnology, Moscow, Russia)

Chapter 3. Enzymatic Electrochemical Biosensors Based on Carbon Paste Electrodes Modified with Polyphenol Oxidase Enzymes for Rutin Detection
(Gabriela Pereira Nunes dos Santos, Ramon Silva Vilela, Stephen Rathina Benjamin, Katia Flavia Fernandes and Flavio Colmati, Instituto de Química, Universidade Federal de Goiás, Goiânia, GO, Brasil, and others)

Index

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