An Essential Guide to Cytogenetics

Naomi Norris and Carmen Miller (Editors)

Series: Genetics – Research and Issues
BISAC: SCI029000

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An Essential Guide to Cytogenetics explores the use of cytogenetic data for studies of frogs as well as the insights that hypotheses of phylogenetic relationships have added to this issue. The authors provide an overview of PcP190 satellite DNA, sex chromosome systems and B chromosomes found in Anura. This book also aim to establish the health effects of various activities and exposures by examining the levels of exposure and the biological effects resulting from the interaction between the organism and the chemical agent. Following this, a chapter is included which focuses on on the complex karyotype issues in myelodysplastic diseases, leukemias, lymphomas and multiple myelomas as the authors see them in daily practice in their center. The authors investigate hybridization, suggesting that the viability of a hybrid between species with a chromosomal discrepancy may offer important hypotheses to explain the morphological, molecular, and cytogenetic diversity of the genus. Trichorhinophalangeal syndrome is analyzed, suggesting that in cases of cytogenetically-invisible alterations, parental FISH analysis as well as aCGH should be considered as part of the clinical baseline testing.

Preface

Chapter 1. Anuran Cytogenetics: An Overview
(Cíntia Pelegrineti Targueta, Stenio Eder Vittorazzi, Kaleb Pretto Gatto, Daniel Pacheco Bruschi, Ana Cristina P. Veiga-Menoncello, Shirlei M. Recco-Pimentel, and Luciana Bolsoni Lourenço, Department of Structural and Functional Biology, University of Campinas (Unicamp), Campinas, São Paulo, Brazil, and others)

Chapter 2. Human Cytogenetic Biomonitoring
(Armanda Teixeira-Gomes, Solange Costa, and João Paulo Teixeira, EPIUnit – Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal, and others)

Chapter 3. Complex Karyotypes and Their Detection in Hematologic Malignancies: The Ongoing Role for Classical Cytogenetics
(Helena Urbankova, PhD, Department of Hemato-Oncology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Olomouc, Czech Republic)

Chapter 4. Natural Hybridizatoin between Chromosomal Discrepant Species and the Role of Hybrid Speciation in the Genus Astyanax
(Francisco de Menezes Cavalcante Sassi, Snaydia Viegas Resende, Rubens Pazza, and Karine Frehner Kavalco, Laboratório de Genética Ecológica e Evolutiva, Universidade Federal de Viçosa, Campus Rio Paranaíba, Rio Paranaíba, MG, Brasil)

Chapter 5. Trichorhinophalangeal Syndrome (TRPS) Revisited
(N. Selenti, M. Tzetis, E. Tsoutsou, and H. Fryssira, Department of Medical Genetics, National and Kapodistrian University of Athens, School of Medicine, Aghia Sophia Children’s Hospital)

Index

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