Amyotrophic Lateral Sclerosis: From Diagnosis to Treatment

Julie Sørensen (Editor)

Series: Neuroscience Research Progress
BISAC: MED057000



Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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Amyotrophic Lateral Sclerosis: From Diagnosis to Treatment focuses on two aspects of neuroimaging related to amyotrophic lateral sclerosis that have greatly evolved in the last decades: the development of optical tools in the biology field and advances in the field of magnetic resonance imaging.

Therapeutic writing and expressive disclosure interventions have been demonstrated to facilitate the emotional processing of thoughts and feelings about the amyotrophic lateral sclerosis experience, with relevant implications for illness adjustment.

Based on these premises, the authors explore the linguistic patterns in the cognitive-affective processing of illness experience in people with amyotrophic lateral sclerosis.

Following this, the authors discuss recent studies that offer a new perspective on sensory networks in motor neuron diseases to understand the true extent and patophysiology of amyotrophic lateral sclerosis and suggest new potential biomarkers for the diagnosis of this tragic disease.

The closing study focuses on the respiratory involvement of amyotrophic lateral sclerosis, which is the principal cause of death. Amyotrophic lateral sclerosis is characterized by respiratory failure consequent to respiratory muscles dysfunction, as well as bulbar muscles which support the upper airways, developing in dyspnoea and impaired sleep.


Chapter 1. Neuroimaging in Preclinical Models of ALS
(Rodolfo G. Gatto, MD, PhD, and Carina Weissmann, PhD, Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, US, and others)

Chapter 2. Linguistic Patterns in the Cognitive-Affective Processing of Illness Experience: A Case-Control Study of Patients with Amyotrophic Lateral Sclerosis
(Andrea Caputo, Department of Dynamic and Clinical Psychology, “Sapienza” University of Rome, Rome, Italy)

Chapter 3. Sensory Denervation in Motor Neuron Disease
(Baris Isak, Department of Neurology/Clinical Neurophysiology, Marmara University, Istanbul, Turkey)

Chapter 4. Non-Invasive Ventilation in ALS
(Maurizia Lanza, Anna Annunziata and Giuseppe Fiorentino, Unit of Respiratory Physiopathology, Monaldi Hospital, Naples, Italy)


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