Alzheimer’s Disease: Risk Factors, Diagnosis, Coping and Support


Brooke Howell (Editor)

Series: Neurology – Laboratory and Clinical Research Developments
BISAC: MED056000

Alzheimer’s disease (AD) is the most common form of senile dementia worldwide. Anosognosia, a deficit in self-awareness, is recognized as one of the core symptoms of Alzheimer’s disease dementia, in which self-awareness gradually deteriorates with disease progression. Chapter one of this book discusses anosognosia in Alzheimer’s disease. Chapter two examines whether pathological narcissistic personality predicts increased risk of neuropsychiatric symptoms in AD.

Chapter three discusses the impairment of instrumental activities of daily living in mild-to-moderate AD patients. Chapter four studies the single nucleotide polymorphisms (SNPs) in four candidate genes, and compares their frequencies in healthy individuals with the frequencies in Venezuelans diagnosed with AD. Chapter five studies the role of IL-6 genotypes in the late-onset of AD. The last chapter evaluates the risk factors and protective factors for impairment in elderly individuals living in communities in Shanghai.
(Imprint: Nova Biomedical)

Table of Contents

Table of Contents


Chapter 1
Anosognosia in Alzheimer’s Disease Dementia
(Yohko Maki, Tomoharu Yamaguchi, and Haruyasu Yamaguchi, National Center for Geriatrics and Gerontology, Aichi, Japan, and others)

Chapter 2
Neuropsychiatry and Dementia. Neuropsychiatric and Behavioral Symptoms in Alzheimer´s Disease. Pathological Narcissistic Personality as a Risk Factor
(Daniel Serrani, Department of Psychobiology, Faculty of Psychology, National University of Rosario, Rosario, Santa Fe, Argentina)

Chapter 3
Impairment of Instrumental Activities of Daily Living in Mild-to-Moderate Alzheimer’s Disease
(Laïla El Amrani, and Martine Simard, School of Psychology, University Laval, Quebec City, Canada, and others)

Chapter 4
Candidate Genes and Late-Onset Alzheimer Disease
(Mercedes Fernández-Mestre and Nemesio Cedeño, Centro de Medicina Experimental “Miguel Layrisse”, Instituto Venezolano de Investigaciones Científicas (I.V.I.C.), Carretera Panamericana, Venezuela)

Chapter 5
The Role of IL6 Genotypes in Late-Onset Alzheimer Disease
(Mercedes Fernández-Mestre, Noslen Lobo, Violeta Ogando and Carlos D. Ramírez, Centro de Medicina Experimental “Miguel Layrisse,” Instituto Venezolano de Investigaciones Científicas (I.V.I.C.), Caracas, Venezuela, and others)

Chapter 6
The Relevant Risk Factors for Cognitive Impairment in Shanghai Community Dwellers, China
(Cece Yang, Tao Wang, Jinghua Wang, Minjie Zhu, Xia Li and Shi Fu Xiao, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Alzheimer’s Disease and Related Disorders Center Shanghai Jiaotong University, Shanghai, China)


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