Alginic Acid: Chemical Structure, Uses and Health Benefits


Adrianna Moore (Editor)

Series: Chemistry Research and Applications
BISAC: SCI013000

Alginate is a natural, anionic polysaccharide typically obtained from brown seaweed but it can be synthesized by some bacteria. It is a water-soluble, linear copolymer consisting of two kinds of alternating blocks, guluronic acid (G block) and mannuronic acid (M block) units, that are irregularly arranged in GG, MG, and MM blocks, while the ratio and pattern of guluronate to mannuronate blocks varies depending on the natural source of alginate.

Most favorable properties of alginate are its biocompatibility, low toxicity, relatively low cost, and mild and easy gelation. Alginates in the presence of divalent cations (mostly calcium cations) very quickly form a hydrogel, polymeric networks with three-dimensional configuration, capable of imbibing high amounts of water. This book discusses the chemical structure, the uses, and health benefits of alginic acid.
(Imprint: Nova)



Table of Contents


Chapter 1 – Alginic Acid: Effectiveness in Treatment of Gastroesophageal Reflux Disease (pp. 1-18)
Rouzbeh Shams, Edward C. Oldfield IV and David A. Johnson (Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA United States, and others)

Chapter 2 – Alginate-Based Drug Carriers: Recent Advances (pp. 19-58)
A. Martínez, E. Pérez, N. Montero, C. Teijón, R. Olmo and M. D. Blanco (Polymeric Materials Group for the Controlled Release of Bioactive Compounds in Biomedicine. Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain, and others)

Chapter 3 – Alginic Acid: Sources, Modifications and Main Applications (pp. 59-120)
Milan Milivojevic, Ivana Pajic-Lijakovic, Steva Levic, Viktor Nedovic and Branko Bugarski (Department of Chemical Engineering, Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia, and others)

Chapter 4 – Vibrational Spectroscopy Characterization of Sodium Alginate and Its Heteropolymeric and Homopolymeric Block Fractions (pp. 121-140)
Betty Matsuhiro, Fabián Martínez-Gómez and Andrés Mansilla (Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile, and others)

Chapter 5 – Immobilization of P. putida A (ATCC 12633) Cells Using Ca-alginate: Environmental Applications for the Removal of Cationic Surfactants Pollutants in Industrial Wastewater (pp. 141-156)
Gloria I. Lucchesi, María F. Bergero, Paola S. Boeris, Gastón A. López, Romina M. Heredia and Andrés S. Liffourrena (Departamento de Biología Molecular, Facultad de Ciencias Exactas, Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Río Cuarto, Córdoba, Argentina)

Chapter 6 – Alginate Utility in Edible and Non Edible Film Development and the Influence of Its Macromolecular Structure in the Antioxidant Activity of a Pharmaceutical/Food Interface (pp. 157-228)
María Dolores De’Nobili, Lucrecia María Curto, José María Delfino, Carolina Daiana Pérez, Dana Bernhardt, Lía Noemí Gerschenson, Eliana Noemí Fissore and Ana María Rojas (Departamento de Industrias, School of Natural and Exact Sciences (FCEN), University of Buenos Aires (UBA). Ciudad Universitaria, Intendente Güiraldes, Buenos Aires, Argentina, and others)

Chapter 7 – Shrinkage-Gelation-Technique-Based Monodispersed Spherical Alginate Gel Bead Formation and Applications (pp. 229-252)
Hirotada Hirama, Kyouhei Aketagawa and Toru Torii (Department of Human and Engineered Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo, Japan)

Chapter 8 – Utilization of Alginate and Alginate-Derived Oligosaccharides Degraded by Bacillus sp. (pp. 253-290)
Joong Kyun Kim, Eun Jung Kim and Da Som Kang (Department of Biotechnology and Bioengineering, Pukyong National University, Busan, Korea)


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