Age-Related Macular Degeneration: Prevalence, Risk Factors and Clinical Management


Melanie Carter (Editor)

Series: Eye and Vision Research Developments
BISAC: MED064000

Age-related macular degeneration (AMD) is the leading cause of blindness in individuals older than 65 years of age. The authors of this book discuss the role of genetics, sunlight, diet, cardiovascular factors, smoking and alcohol as possible risk factors for AMD. Furthermore, the dry form is more common and accounts for about 85-90% of AMD patients in the USA, while Japanese AMD patients predominantely progress to wet-form or polypoidal choroidal vasculopathy (PCV). The function of a serine protein gene, HTRA1, in wet-form AMD patients is explored in detail. Conversely, the final chapter evaluates the therapeutic effects of high omega-3 fatty acids as anti-inflammatory agents in dry AMD patients. The preliminary findings indicate a promising therapeutic regime for dry AMD and perhaps for other retinopathies as well.
(Imprint: Nova Biomedical)

Table of Contents

Table of Contents


Chapter 1
Overview of Risk Factors for Age-Related Macular Degeneration (AMD)
(Richard A. Armstrong and Maryam Mousavi, Vision Sciences, Aston University, Birmingham, UK, and others)

Chapter 2
HTRA1 Overexpression Induces the Exudative Form of Age-Related Macular Degeneration
(Daisuke Iejima, Mao Nakayama and Takeshi Iwata, Division of Molecular and Cellular Biology, National Institute of Sensory Organs, National Hospital Organization Tokyo Medical Center, Tokyo, Japan)

Chapter 3
The New Era of Omega-3 Fatty Acids Supplementation: Therapeutic Effects on Dry Age-Related Macular Degeneration
(Tassos Georgiou and Ekatherine Prokopiou, Ophthalmos Research and Educational Institute, Nicosia, Cyprus)



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