Table of Contents
Table of Contents
Preface
Anticancer
Chapter 1. Mitogen-Activated Protein Kinase (MAPK) Inhibitors for The Treatment of Advanced Hepatocellular Carcinoma
Srikanta Dash, Srinivas Chava, Yucel Aydin, Joseph J. Buell, Tong Wu, Ari J. Cohen, Luis A. Balart (Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New Orleans, Lousiana, United States of America, and others)
Chapter 2. Protein Farnesyltransferase Inhibitors as Novel Anticancer Chemotherapeutics
Manish K. Gupta, Dheeraj Kumar Sharma and Ravindra K. Rawal (School of Pharmacy, Lloyd Institute of Management and Technology, Knowledge Park-II, Greater Noida-201306, UP, India, and others)
Chapter 3. Peptidylarginine Deiminase (PAD) Inhibitors
Adam Koebel, Elizabeth Joanne Curiel Tejeda, Rhonda Tu, and Lakshmi P. Kotra (Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada, and others)
Chapter 4. Interfering with Enzymatic Steps of Micrornas Pathway Using Small Molecules
Maria Duca, Université Côte d’Azur (Institute of Chemistry of Nice UMR7272 CNRS, Faculté des Sciences, Parc Valrose, Nice, France)
Chapter 5. In Silico Studies for the Discovery of Leads to Inhibit Cyclin-Dependent Kinase 2 (CDK2)
Murali Aarthy, Singaravelu Usha and Sanjeev Kumar Singh (Computer Aided Drug Design and Molecular Modelling Lab, Department of Bioinformatics, Science campus, Alagappa University, Karaikudi, India)
Chapter 6. Design and Development of Tyrosine Kinase Inhibitors as Anticancer Drugs
Basheerulla Shaik, Satya P. Gupta and Vijay K. Agrawal (Department of Applied Sciences, National Institute of Technical Teachers’ Training & Research, Shamla Hills, Bhopal, Madhya Pradesh, India, and others)
Chapter 7. In Silico Design of Carbonic Anhydrase Inhibitors as Antitumor Drugs
Shalini Singh, Basheerulla Shaik and Satya P. Gupta (QSAR & Cheminformatics Laboratory, Department of Chemistry, Bareilly College, Bareilly,(U.P.) India, and others)
Antiviral
Chapter 8. Studies on Inhibitors of Dengue Virus Protease
Venkatesan Jayaprakash, Ajay Kumar Timiri and Barij Nayan Sinha (Department of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, India)
Chapter 9. Design and Development of Inhibitors of Picornavirus Proteases
Debasis Das (Department of Chemistry, Sree Chaitanya College, Habra, Parganas, West Bengal, India)
Chapter 10. Neuraminidase Inhibitors: From Research Tools to Drug Candidates
Vaishali M. Patil and Satya P. Gupta (Department of Medicinal Chemistry, Kharvel Subharti College of Pharmacy, Swami, Vivekanand Subharti University, Subhartipuram, Meerut, India, and others)
Chapter 11. Recent Developments in HIV-1 Integrase Inhibitors
Utsab Debnath and Seturam B. Katti (Medicinal and Process Chemistry Division,CSIR-Central Drug Research Institute, Lucknow, India)
Chapter 12. Studies on Dual Inhibitors of HIV Reverse Transcriptase and Integrase
Subramanian Karunagaran, Ramanathan Shylaja and Chandrasekaran Meganathan (Department Physics, G.K.M. College of Engineering & Technology, Alapakkam, Mappedu Road, Perungalathur, Tamil Nadu, India)
About the Editor
Index