Advances in Natural Products Discovery


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Series: Chemistry Research and Applications
BISAC: SCI013000

The largely unexplored natural world harbors great biodiversity, and provides a unique and rich source of natural products with interesting pharmaceutical activities as well as potential applications for environmental protection. Over the last few years, much attention has been paid to unraveling the structural, compositional and sequential properties of bioactive compounds, but the exploration of new natural resources needs to be developed wisely while keeping sustainability principles in mind. With the help of some developed isolation techniques, researchers have been able to elucidate new extraction methods applicable to both aquatic and terrestrial organisms.
Natural products have often been used in medicine, food, fragrances, and pest control. Most likely due to their easy accessibility, terrestrial plants have been the major source of medicinal products, especially for traditional or folk medicine. However, only 10% of over 250,000 plants have been investigated for biological activity. On the other hand, aquatic environments contain over 80% of world’s plant and animal species. In recent years, several bioactive compounds have been extracted from various marine organisms, such as tunicates, sponges, starfish, soft corals, bryozoans, and sea cucumbers, among others. The search for new metabolites from marine organisms has resulted in the isolation of more than 10,000 metabolites, many of which are endowed with pharmacodynamic properties. These natural products are of high commercial value due to their natural source, complete biodegradable properties, lower or no toxicity, and in most cases lower cost compared to synthetic chemicals. Despite the biodiversity in the marine environment overcoming that of the terrestrial environment, the research into the use of natural marine products as pharmaceutical agents and for environmental applications is still in its early stages.
In this context, this book highlights some of the most recent advances in natural product discovery over the past few years. (Imprint: Nova)

Table of Contents

Table of Contents


Chapter 1. Bioactive Natural Compounds: Biological Significance and Clinical Implementation in Organ Pathophysiology
Sudip Bhattacharyya, Sayantani Chowdhury and Parames C. Sil (Division of Molecular Medicine, Bose Institute, Calcutta, West Bengal, India)

Chapter 2. Natural Therapeutics against Alzheimer’s Disease: Conventional Treatment versus Phytotherapy
Abhijit Dey and Anuradha Mukherjee (Department of Biological Sciences, Presidency University, Kolkata, India, and others)

Chapter 3. Bioactive Constituents from Artocapus
Rohaya Ahmad and Mohd Nazrul Hisham Daud (Faculty of Applied Sciences, Universiti Teknologi MARA, Shah Alam, Selangor, Malaysia, and others)

Chapter 4. Maize (Zea mays L.) – An Ethnopharmacological Review
Marcelo Maraschin, Simone Kobe de Oliveira, Maria Beatriz da Rocha Veleirinho, Priscilla Maria Menel Lemos, Aline Pereira, Rosedo Augusto Yunes, Ivonne Delgadillo, and Shirley Kuhnen (Plant Morphogenesis and Biochemistry Laboratory – Federal University of Santa Catarina, Florianopolis, SC, Brazil, and others)

Chapter 5. Antitumor Sesterterpenoids
Lishu Wang, Junfeng Wang and Yonghong Liu (CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China, and others)

Chapter 6. Recently Studies of Polar Steroids from Starfish: Structures, Biological Activities and Biosynthesis
Natalia V. Ivanchina, Alla A. Kicha, Timofey V. Malyarenko, Valentin A. Stonik (G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, Vladivostok, Russia)

Chapter 7. Strategies based in Microbial Metabolites for Microbial Control in Industrial Water Systems
Vera Lúcia dos Santos and Andrea Sousa Monteiro (Department of Microbiology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte-MG, Brazil, and others)

Chapter 8. Strategies based in Microbial Metabolites for Microbial Control in Agriculture
Vera Lúcia dos Santos and Andrea Sousa Monteiro (Department of Microbiology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte-MG, Brazil, and others)


Additional Information

The principal audiences will be natural product chemists, medicinal chemists, analytical chemists, organic chemists, biologists, food scientists, environmental scientists, and pharmacologists as well as post-graduate students, researchers, and lecturers.

Additional information



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