Advances in Medicine and Biology. Volume 96

Leon V. Berhardt

Series: Advances in Medicine and Biology
BISAC: MED000000



Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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The chapters in this volume of “Advances in Medicine and Biology,” present the latest research in medical research. The first chapter provides recent findings from animal studies and human intervention studies are reviewed and evaluated with respect to the preventive/protective effects of cranberries against metabolic syndrome, type-2 diabetes, and cardiovascular disease.

Chapter Two discusses the use of the North American cranberry to decrease matrix metalloproteinase activity in aortic smooth muscle cells in vitro, which occurs via modulation of key cellular signaling activities.

Chapter Three examines how dietary whole cranberry modulates plasma cholesterol profiles and prevents liver toxicity in response to cholesterol-feeding in the JCR.

Chapter Four discusses the known characteristics and functions of macrovascular pericytes and describes the role of these cells in the development of atherosclerotic lesions.

Chapter Five reviews the putative role of pericytes in thyroid gland and rare/orphan thyroid tumors.

Chapter Six discusses the synthesis, regulation and physiological effects of the luteinizing and follicle-stimulation hormones in women.

Chapter Seven presents the epidemiology of legionellosis as well as clinical features and control strategies of the microorganism.

Chapter Eight provides insights on neuronal vulnerability and astrocytic abnormalities during stroke.

Chapter Nine provides an overall perspective of Chronic Kidney Disease (CKD) and the potential role of the Scientist in the Community.

Chapter Ten describes the active regulatory process that maintains corneal avascularity, describes the pathogenesis of the neovascular process, provides an overview of the most common aetiologies of corneal neovascularization (CoNV), as well as current and future treatments available.

Chapter Eleven describes the clinical, histological, and molecular changes occurring in the skin after ultraviolet radiation (UVR) exposure, and reviews the specific cellular and biochemical mechanisms contributing to the clinical phenotype of photoaged skin. The last chapter studies medication error reduction at transitions of care through a better multiciplinary intervention.
(Imprint: Nova Biomedical)


Chapter 1
Cranberry (Vaccinium macrocarpon) and Metabolic Syndrome
(Tongtong Xu, Sige Zou, Joshua D. Lambert, and Yaning Sun, Department of Food Science, Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, PA, USA, and others)

Chapter 2
North American Cranberry (Vaccinium macrocarpon) Mediated Decreases in Matrix Metalloproteinase Activity in Aortic Smooth Muscle Cells in vitro Occurs via Modulation of Key Cellular Signaling Activities
(Amanda Thomas, Kunal Patel, Catherine Neto and Robert Hurta, Department of Biology, University of Prince Edward Island, Charlottetown, PE, Canada, and others)

Chapter 3
Dietary Whole Cranberry (Vaccinium macrocarpon) Modulates Plasma Cholesterol Profiles and Prevents Liver Toxicity in Response to Cholesterol-Feeding in the JCR:LA-cp Corpulent Rat Model
(Colin Stetson, Colleen MacDougall, Anne Liberty, Catherine Neto, Katherine Gottschall-Pass and Robert Hurta, Department of Biology, University of Prince Edward Island, Charlottetown, PE., Canada, and others)

Chapter 4
Pericytes: Cell Biology, Functions and Role in Human Atherogenesis
(Alexander N. Orekhov, Ekaterina A. Ivanova, Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, Russian Academy of Sciences, Moscow, Russia, and others)

Chapter 5
Putative Role of Pericytes in Thyroid Gland and Rare/Orphan Thyroid Tumors
(Danica Vodopivec and Carmelo Nucera, Laboratory of human thyroid cancers preclinical and translational research, Division of Cancer Biology and Angiogenesis, Cancer Research Institute (CRI), Cancer Center, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA)

Chapter 6
Luteinizing and Follicle-Stimulating Hormones in Women: Synthesis, Regulation and Physiological Effects
(M.R. Espejo-Catena, N. Veiga Canuto, Instituto FIVIR, Institute of Assisted Reproduction, Valencia, Spain, and others)

Chapter 7
Legionellosis: Epidemiology, Clinical Features and Control Strategies
(Enrique Gea-Izquierdo, Pontifical Catholic University of Ecuador, Faculty of Medicine, Quito, Ecuador, University of Málaga, Chair of Work Safety and Health, Málaga, Spain)

Chapter 8
Stroke-Prone Spontaneously Hypertensive Rats: Insights on Neuronal Vulnerability and Astrocytic Abnormalities in Stroke
(Kazuo Yamagata, Department of Food Bioscience and Biotechnology, College of Bioresource Sciences, Nihon University (NUBS), Kameino, Fujisawa, Kanagawa, Japan)

Chapter 9
The Role of the Scientist in Community: Intertwining Immunology and Biochemistry Perspectives on Chronic Kidney Disease (CKD)
(Muhammad S, Antonopollos A, Mathews D, Oliver J, The Renal Patient Support Group (RPSG), England UK, and others)

Chapter 10
Corneal Neovascularization: Update on Pathogenesis and Advances in Treatment Strategies
(Behaegel J, Ni Dhubhghaill S, Koppen C, Zakaria N, Centre for Cell Therapy and Regenerative Medicine UZA, Antwerp, Belgium, and others)

Chapter 11
Mechanisms of Photoaging
(Jeffrey F. Scott, Elma Baron, and Meg R. Gerstenblith, Department of Dermatology, University Hospitals Case Medical Center and Case Western Reserve University, Cleveland, OH, USA)

Chapter 12
Medication Error Reduction at Transitions of Care through a Better Multiciplinary Intervention
(Ana Fajreldines, Laura Davide, Diego Bernárdez, Marcelo Pellizzari, Austral University Hospital – Argentina, and others)


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