Advances in Medicine and Biology. Volume 193


Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology
BISAC: MED000000

This volume includes eight chapters detailing recent advances in the fields of medicine and biology. Chapter One reviews in vitro animal and clinical findings on the antioxidant properties of Crocus sativus L. and its constituents. Chapter Two discusses advances in the possible role of non-selective channels in muscular denervation and dystrophies. Chapter Three presents a standardization of a testicular irradiation protocol in rats and an assessment of the histopathological and morphometric-stereological changes on the testes and epididymis, and vitality, concentration, and morphology of sperm according to a crescent curve of ionizing radiation dose, which is relevant for cancer treatments. Chapter Four describes the classical aspects of bovine mastitis and its underlying gene networks. Chapter Five reviews the etiologies, pathophysiology, and diagnostic work-up of acute aortic regurgitation and highlights key principles in its management. Chapter Six assesses the advantages and disadvantages of different surgical options for Charcot-Marie-Tooth disease. Chapter Seven provides an overview of molecular mechanisms responsible for the development of urticaria as well as molecular therapeutic agents under development for the treatment of urticaria. Finally, Chapter Eight describes recent guidelines for diagnosis and management of various types of urticaria.

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Table of Contents


Chapter 1. Antioxidant Effects of Crocus sativus L. and its Derivatives, Basic and Clinical Evidences
(Mohammad Hossein Boskabady, Saeideh Saadat, Zahra Ghasemi, Arghavan Memarzia and Mohammad Reza Aslani – Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran, et al.)

Chapter 2. Advances in the Possible Role of Non-Selective Channels in Muscular Denervation and Dystrophies
(Walter Vásquez, Macarena Díaz-Ubilla, Luis A. Cea and Juan C. Sáez – Departamento de Fisiología, Pontificia Universidad Católica de Chile, Santiago, Chile, et al.)

Chapter 3. Standardization of Experimental Model of Testicular Injury Induced by Ionizing Radiation in Preclinical Studies
(Maria Angélica Spadella, Marco G. Alves, Ligia Gonçalez de Paiva, Lais L. Manção dos Santos and Agnaldo Bruno Chies – Laboratory of Human Embryology, Marília Medical School – FAMEMA, Marília, SP, Brazil, et al.)

Chapter 4. Gene Networks Underlying Bovine Mastitis
(Aarti Adhikari, Disha Pant, and Neha – Department of Veterinary Pharmacology and Toxicology, G. B. Pant University of Agriculture and Technology, Pantnagar, India, et al.)

Chapter 5. Acute Aortic Regurgitation: An Overview
(Darren C. Tsang and Siu-Hin Wan – Division of Cardiology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX, US)

Chapter 6. Anesthetic Management in Charcot-Marie-Tooth Disease
(Monica del-Rio-Vellosillo, Jose Javier Garcia-Medina, Maria del Carmen Martinez-Segovia and Antonio Abengochea-Cotaina – Senior Consultant Anesthetist, Department of Anesthesia, University Hospital Virgen de la Arrixaca, El Palmar, Murcia, Spain, et al.)

Chapter 7. Molecular Mechanisms Involved in the Pathogenesis of Urticaria and Future Therapeutic Prospects
(Mahak Masoodi, Fizalah Kawoosa, Afaq H Beigh, Zafar A Shah and Roohi Rasool – Department of Immunology and Molecular Medicine, Sher I Kashmir Institute of Medical Sciences, India)

Chapter 8. Diagnosis and Management of Urticaria: Current Guidelines and Protocols
(Mahak Masoodi, Fizalah Kawoosa, Afaq H Beigh, Zafar A Shah and Roohi Rasool – Department of Immunology and Molecular Medicine, Sher I Kashmir Institute of Medical Sciences, India)


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