Advances in Medicine and Biology. Volume 188


Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology
BISAC: SCI008000

This edited manuscript includes six chapters, each describing recent advancements in medicine and biology. Chapter One investigates the impact on psychopathology of adding lurasidone to clozapine for people with treatment-resistant schizophrenia. Chapter Two reviews some intestinal protozoa and their diseases in immunodeficient patients. Chapter Three addresses the general role of inflammasomes and reviews current knowledge of potential therapeutic application of inflammasomes in neurological disorders. Chapter Four looks at the role of ion channel activation and downstream signal transduction in modulating Sertoli cell behavior to a final physiological response and its potential impact on spermatogenesis. Chapter Five includes a comprehensive view on sulfur-containing saponins and their mode of actions. Lastly, Chapter Six assesses the pathophysiological impacts of Spironucleus salmonis infection on the seawater adaptability of juvenile chum salmon.

Table of Contents


Chapter 1. Add-on of Luradsidone to NHRF-Hosted Treatment-Resistant Persons with Schizophrenia: Outcomes from the Real World
(Alessandro De Risio – NHS, Health Trust n. 4 “Veneto Orientale,” Unit of Psychiatry, Community Mental Health Centre of Portogruaro, Portogruaro, Venice, Italy)

Chapter 2. Enteric Protozoan Infections in Immunodeficient Patients
(Khadijeh Khanaliha – Research Center of Pediatric Infectious Diseases, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran)

Chapter 3. Therapeutic Application of Targeting Inflammasome Signalling Pathway in Neurological Disorders
(So Yeong Cheon – Department of Biotechnology, College of Biomedical& Health Science, Konkuk University, Chungju, Republic of Korea)

Chapter 4. Physiological Functions of Potassium and Chloride Channels through Non-Classical Hormone Signal Transduction in Sertoli Cells: Clinical Significance
(Danusa Menegaz, Ana Karla Bittencourt Mendes and Fátima Regina Mena Barreto Silva – Departamento de Bioquímica – Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Trindade, Florianópolis, SC, Brazil, et al.)

Chapter 5. Sulfur-Containing Saponins and Their Biological Activities: A Review
(Idris Arslan – Zonguldak Bülent Ecevit University, Biomedical Engineering, Incivez, Zonguldak, Turkey)

Chapter 6. Pathophysiological Impacts of Diplomonad Flagellate Spironculeus salmonis Infection on Seawater Adaptability of Juvenile Chum Salmon Oncorhynchus keta
(Shinya Mizuno and Shigehiko Urawa – Salmon and Freshwater Fisheries Research Institute, Hokkaido Research Organization, Eniwa, Japan, et al.)


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