Advances in Medicine and Biology. Volume 178


Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology

BISAC: MED000000

This monograph includes seven chapters that describe recent advances in medicine and biology. Chapter One discusses glutathione transferases (GSTs) from helminth parasites in the host-parasite interaction and candidates for vaccine development targeting parasitic GSTs. Chapter Two reviews the pharmacological and therapeutic effects of onion and its constituents in allergic and immunologic disorders. Chapter Three discusses state-of-the-art knowledge of apolipoprotein E (ApoE) polymorphism to demonstrate its wide biological properties and its effects on how medical conditions can be managed. Chapter Four introduces the antiviral and immunomodulatory effects of macrolides and the associated mechanisms in the human airway and lung cells. Chapter Five evaluates the role of several genes that are likely to be involved in diabetic neuropathy by employing transcriptome analysis. Chapter Six details diagnosis, risk factors, and treatment of nephrotic syndrome, the frequent cause of chronic kidney diseases observed in children and adults. Finally, Chapter Seven describes the characteristics of the Michigan Cancer Foundation-7 (MCF-7) cell line and its significant role in the anticancer research paradigm.

Table of Contents


Chapter 1. Glutathione Transferases from Helminth Parasites in the Host-Parasite Interaction
(Cora Chalar and Veronica Fernandez – Sección Bioquímica, Departamento de Biología Celular y Molecular, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay, et al.)

Chapter 2. The Effects of Allium cepa and Its Constituents in Allergic and Immunologic Disorders
(Mohammad Hosein Boskabady, Sima Beigoli, Sepideh Behrouz, Arghavan Memar zia, Seyyedeh Zahra Ghasemi and Marzie Boskabady – Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran, et al.)

Chapter 3. Apolipoprotein E Polymorphism Effects on Human Health and Disease
(Caíque Silveira Martins da Fonseca, Breno da Nóbrega Bezerra, Luanna Sales da Costa and Vera Lúcia de Menezes Lima – Grupo de Pesquisa em Doenças Metabólicas, Faculdade Tiradentes de Jaboatão dos Guararapes, Jaboatão dos Guararapes, PE, Brazil, et al.)

Chapter 4. Anti-viral, Anti-inflammatory and Immunomodulatory Effects of Macrolides and Their Mechanisms in the Human Airway and Lung Cells
(Mutsuo Yamaya and Shoji Kudoh – Department of Respiratory Medicine, Tohoku University School of Medicine, Sendai, Japan, et al.)

Chapter 5. Electrophysiologic and Transcriptome Analysis in Cases of Prediabetic/Asymptomatic Diabetic and Diabetic Persons with Neuropathy
(S. H. Talib, Yusuf Talib and G. Punde – Dept of Medicine, MGM Medical College and Hospital, Aurangabad, India, et al.)

Chapter 6. Nephrotic Syndrome: Diagnosis, Risk Factors and Treatment
(Jinal M. Thakor and Kinnari N. Mistry – Ashok and Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences, Vallabh Vidyanagar, Anand, Gujarat, India)

Chapter 7. The MCF-7 Cells: Advances in Research and Future Directions
(Shadab Miyan Siddiqui, Abdul Roouf Bhat, and Fareeda Athar – Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India, et al.)


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