Advances in Medicine and Biology. Volume 177


Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology

BISAC: MED000000

This compilation comprises 6 chapters, each detailing a recent advancement in medicine and biology. Chapter 1 deals with tuberculosis (TB), describing current knowledge of disease pathogenesis, epidemiology of TB and drug-resistant TB, evolution and molecular mechanisms of drug resistance, fitness compensatory mechanisms and laboratory methods for the diagnosis of susceptible and drug-resistant TB. Chapter 2 details the use of B cell-targeted therapy for treatment of autoimmune and chronic inflammatory diseases. Chapter 3 concerns peptic ulcer disease and the various therapeutic approaches used to treat ulcers or lesions in the gastrointestinal tract. Chapter 4 discusses the efficacity of in vitro cultures of Astragalus for biomass and secondary metabolite production. Chapter 5 describes the B lymphocyte activation factor (BAFF), a potent cell-survival factor expressed in many hematopoietic cells. Finally, Chapter 6 presents a review of the literature to determine the relationship between non-alcoholic fatty liver disease, non-alcoholic steatohepatitis and hepatocellular carcinoma to establish a guideline for monitoring patients.

Table of Contents


Chapter 1. Mycobacterium tuberculosis: Epidemiology, Pathogenesis, Diagnosis and Drug-Resistance Mechanisms
(Noura M. Al-Mutairi, Suhail Ahmad and Eiman Mokaddas – Department of Microbiology, Faculty of Medicine, Kuwait University, Safat, Kuwait)

Chapter 2. B Cell Activating Factor (Baff) as Therapeutic Target in Autoimmune and Chronic Inflammatory Diseases
(Ota Fuchs – Institute of Hematology and Blood Transfusion, Prague, Czech Republic)

Chapter 3. Pathophysiological Implications of the Peptic Ulcer Disease and Its Therapeutic Approaches
(Chitrakshi Consul, Virendra Singh and Sonu Chand Thakur – Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India)

Chapter 4. In Vitro Biomass Production of Astragalus Species and Cycloartane Glycosides Accumulation
(Pınar Nartop – Department of Biomedical Engineering, Faculty of Engineering, Tekirdağ Namık Kemal University, Tekirdağ, Turkey)

Chapter 5. Role of B Cell Activating Factor (Baff) in Induction of Anti-apoptotic Nuclear Factor Kappa B (Nf-κb) Expression
(Ota Fuchs – Institute of Hematology and Blood Transfusion, Prague, Czech Republic)

Chapter 6. Non-alcoholic Fatty Liver Disease and Hepatocellular Carcinoma
(Mario Serradilla Martín, MD, Ana Palomares Cano, MD, José Ramón Oliver Guillén, MD, PhD and José Manuel Ramia Ángel, MD, PhD – Department of Surgery, Miguel Servet University Hospital, Zaragoza, Spain, et al.)


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