Advances in Medicine and Biology. Volume 176


Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology

BISAC: MED000000

This compilation comprises 8 chapters, each of which details a recent advancement in medicine and biology. Chapter 1 describes innate immune responses and their role in controlling infections, including the relationship between innate and adaptive immune responses during infections. Chapter 2 focuses on the structural characteristics of transforming growth factor beta (TGF-β) and its diverse biological activities in cancer signaling pathways and presents current information about the role of TGF-β in cancer cell signaling. Chapter 3 summarizes several preceding articles on invasive procedures applied with questionable clinical indications in the former Soviet Union. Chapter 4 provides information about the physical properties, isomerism, synthesis and reactions of thiadiazole, with emphasis placed on the current studies of various syntheses of thiadiazole compounds and their important biological properties. Chapter 5 evaluates the antifungal activity of the leaf ethanolic extract of Persea americana, popularly known as avocado, and its modulatory potential in association with fluconazole to verify its action on Candida micromorphology as well as its chemical characterization. Chapter 6 explores the step-by-step role of TGF-β during the process of wound healing. Chapter 7 describes hypophosphatasemia, a rare pathophysiological condition that causes various diseases, and includes new information about hypophosphatasemia that has assisted with the diagnosis of Kikuchi Fujimoto disease and can help to predict the outcome of cardiac surgery and septic shock. Finally, Chapter 8 summarizes the evolution of digital holography, including the latest results on visualizing and distinguishing different types of blood cells.



Chapter 1. Innate Immune Responses and Their Role in Controlling Infections
(Samuel Victor Nuvor, PhD – Department of Microbiology and Immunology, School of Medical Sciences, University of Cape Coast, Ghana)

Chapter 2. Transforming Growth Factor Beta Structure and Functions Focused on Biological Roles in Cancer Cell Signaling
(Fatemeh Sanjabi, Hosna Babini and Abolfazl Akbari – Department of Medical Biotechnology, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran, et al.)

Chapter 3. Invasive Procedures with Unproven Efficiency
(Sergei V. Jargin, MD – Peoples’ Friendship University of Russia, Moscow, Russia)

Chapter 4. Overview of Thiadiazole Compounds
(Bahittin Kahveci, PhD, and İnci Selin Doğan, PhD – Department of Nutrition and Dietetics, Faculty of Health Sciences, Karadeniz Technical University, Trabzon, Turkey, et al.)

Chapter 5. Persea americana Mill. (Lauraceae): Chemical Composition and Antifungal Effect
(Maria Audilene de Freitas, Jacqueline Cosmo Andrade, Antonia Thassya Lucas dos Santos, Rafael Pereira da Cruz, Josefa Carolaine Pereira da Silva, Erlanio Oliveira de Sousa, Débora Lima Sales, Thiago Sampaio de Freitas, Henrique Douglas Melo Coutinho, Maria Flaviana Bezerra Morais-Braga and Rejane Pereira Neves – Department of Mycology, Federal University of Pernambuco-UFPE, Recife, PE, Brazil, et al.)

Chapter 6. TGF-βeta and Wound Healing
(Kaan Kaltalioglu and Sule Coskun-Cevher – Espiye Vocational School, Giresun University, Giresun, Turkey, et al.)

Chapter 7. Hypophosphatasemia
(Yasuji Inamo, MD, PhD – Center for Child and Adolescent Health, Pediatric Rheumatology and Endocrinology, Jiai Hospital, Tokyo, Japan)

Chapter 8. Evolution of Digital Holography for the Investigation of Blood Cells
(Ann-Kathrin Reichenwallner – Technologies for Precision Medicine, Siemens Healthcare GmbH, Erlangen, Germany)


Additional information