Advances in Medicine and Biology. Volume 174


Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology
BISAC: MED000000

Advances in Medicine and Biology. Volume 174 first provides a systematic review of the synthetic route and biological activities associated with 1,2,4-oxadiazole, 1,2,5-oxadiazole and 1,3,4-oxadiazole derivatives.
The authors discuss recent advances in understanding the enantioselective separation and biological activities of the naturally occurring chiral compounds of essential oils.
Subsequently, orthobiologics are discussed in the context of their potential in the management of early osteoarthritis, particularly focusing on the treatment of cartilage injuries.
Another study aims to improve our understanding of the pathological mechanisms of choroidal neovascularization and approaches how to address the issue in central serous chorioretinopathy.
An overview of the lignocellulolytic enzymes secreted by A. fumigatus during biomass conversion is provided, focusing on the quantitative expression of cellulolytic, hemicellulolytic, and ligninolytic enzymes and their synergetic mechanism during biomass degradation.
The closing report reviews the current literature on metabolic syndrome, exploring the mechanisms proposed to better understand the role of environmental, genetic, and epigenetic aspects in the pathogenesis of this condition.

Table of Contents

Table of Contents


Chapter 1. Biological Activity Spectrum of Oxadiazoles as a Privileged Scaffold in Medicinal Chemistry
(Mange Ram Yadav, Prashant R. Murumkar, Rahul B. Ghuge, Rahul R. Barot, Monica Chauhan and Rasana Yadav, Centre of Research for Development, Parul University, Limbda, Vadodara, Gujarat, India, and others)

Chapter 2. Chiral Synthons from Essential Oils: Enantioselective Separation, Biological Activities and as Chiral Pools for the Synthesis of Natural Products
(Abdelkrim Cheriti, Zakaria Boukhobza,Karima Sekkoum, Noureddine Boulenouar, Houria Djeradi and M. Fouzi Talhi, Phytochemistry and Organic Synthesis Laboratory, Medicinal faculty, UTMB, Bechar, Algeria, and others)

Chapter 3. Orthobiologics to Treat Cartilage Injuries and Early Osteoarthritis in the Hip and Knee
(C. I. Anibueze, W. S. Koh, S. Tsamados, MD, S. Tibrewal, P. K. Jaiswal, MD, Royal Free London NHS Trust, London, UK, and others)

Chapter 4. Choroidal Neovascularization Secondary to Central Serous Chorioretinopathy: Understanding the Pathogenesis and Treatment Approaches
(Samet Gulkas, MD, Pelin Kiyat, MD, and Osman Cekic, MD, Ophthalmology Department, Abdulkadir Yuksel Hospital, Gaziantep, Turkey, and others)

Chapter 5. Aspergillus fumigatus: An Overview of Secretome in the Presence of Biomass
(Sunil S. Adav, Singapore Phenome Centre, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore)

Chapter 6. Role of the Environmental, Genetic and Epigenetic Aspects of the Metabolic Syndrome: A Comprehensive Approach
(Cézane Priscila Reuter, PhD, Caroline Brand, PhD, Pâmela Ferreira Todendi, PhD, Andréia Rosane de Moura Valim, PhD, Parnian Poursafa and Roya Kelishadi, MD, Department of Health Sciences and Graduate Program in Health Promotion, University of Santa Cruz do Sul, Santa Cruz do Sul, Rio Grande do Sul, Brazil, and others)


Additional information



Publish with Nova Science Publishers

We publish over 800 titles annually by leading researchers from around the world. Submit a Book Proposal Now!