In this compilation, the authors review the available evidence of the benefits of benfotiamine administration, paying particular attention to patients with type 2 diabetes mellitus and diabetic peripheral neuropathy, cardiac autonomic neuropathy and gastrointestinal neuropathy.
An overview of cyclic AMP response element binding protein’s structure and functions is provided, in addition to a review of its molecular mechanisms and role in disease processes, including neural diseases, diabetes and cancer.
Based on bibliographic references and studies carried out by the authors, this work also assesses the problem of modular total hip prostheses, regarded as a closed loop biotribosystem.
The best available evidence in the field of dental rehabilitation is discussed, with the goal of constructing a reliable base for the approach of new investigations.
In closing, the authors present the synthesis methods and pharmacological properties of triazole-derived heterocyclic systems. Triazoles are an important class of heterocyclic compounds that are five-membered aromatic azole ring with three nitrogen and two carbon atoms.
Chapter 1. Recent Advances in the Treatment of Neuropathies in Type 2 Diabetes Mellitus Patients: Focus on Benfotiamine (Review and Own Data)
(Viktoria A. Serhiyenko, Ludmila M. Serhiyenko and Alexandr A. Serhiyenko, Department of Endocrinology, Danylo Halitsky Lviv National Medical University, Lviv, Ukraine)
Chapter 2. CREB: Structure, Functions, and Role in Disease
(Yun Yan and Mark A. Clements, Children’s Mercy Kansas City, University of Missouri-Kansas City, School of Medicine, Kansas City, Missouri, US)
Chapter 3. A Suggestive Qualitative Review of the Tribological Implications of Total Hip Prostheses Modularization
(Lucian Capitanu, Liliana-Laura Badita and Constantin Tiganesteanu, Tribology Department, Institute of Solid Mechanics of the Romanian Academy, Bucharest, Romania, and others)
Chapter 4. Variations of Masticatory Efficiency in Dentate Patients and Those Wearing Implant Overdentures, Fixed-Detachable Hybrid Prostheses, and Complete Dentures With and Without Denture Adhesive
(Carlos Torres-Sánchez, DDS, PhD, Vanessa Montoya-Salazar, DDS, , PhD, Jose-Luis Gutierrez-Perez, DMD, PhD, and Daniel Torres-Lagares, DDS, , PhD, Department of Stomatology, Faculty of Dentistry,
University of Seville [US], Seville, Spain)
Chapter 5. Thiazolidinone-Related Heterocyclic Compounds as Potential Therapeutic Agents
(Bushra Khan and Sonu Chand Thakur, Centre for Interdisciplinary Research in Basic Sciences [CIRBSc], Jamia Millia Islamia, New Delhi, India)
Chapter 6. Synthesis and Pharmacological Activities of Triazole Derivatives
(Bushra Khan and Sonu Chand Thakur, Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India)