Advances in Medicine and Biology. Volume 164

Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology
BISAC: MED000000

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Advances in Medicine and Biology. Volume 164 begins by proposing that first-line chemotherapy of metastatic colorectal cancer consensus molecular subtypes appears to be a prognostic factor that is able to provide information about growth rate.

The authors go on to review the current and future applications of bioartificial grafts and conduits in the bridging of peripheral nerve defects.

Ginsenoside Rb1 and phosphoramidon are studied in the zebrafish model of diabetic retinopathy, a progressive proliferative and non-proliferative disorder of retina with alterations of the blood-retinal barrier.

Basic knowledge on the events from follicle development to implantation crucial to achieve successful conception as well as contraception is presented, describing the mechanism of contraceptive action of Chhaya.

Hydroxydaunorubicin, also known as doxorubicin, a metabolite of Streptomyces peucetius and a prominent family member of anthracycline antibiotics is studied.

The authors also review the possible mechanisms by which doxorubicin provokes concomitant side effects and clinical disorders, as well as the damage-assaying biochemical markers and the metabolites in these conditions.

Updated data with a systematic search through the largest medical information databases is used to assess the therapeutic and preventive role in urinary incontinence of pelvic floor rehabilitation in pregnancy and postpartum.

In closing, recent studies on the host and lactic acid bacteria as well as probiotic interactions in terms of molecular and cellular mechanisms of action via signaling pathways, apoptosis, and heat shock proteins are reviewed.

Preface

Chapter 1. Consensus Molecular Subtypes: New Findings to Improve the Initial Management of Patients with Metastatic Colorectal Cancer
(A. Colloca Giuseppe, Venturino Antonella and Guarneri Domenico, Oncologia Medica Imperiese, Imperia, Italy)

Chapter 2. Tissue Engineered Bioartificial Conduits for Bridging Peripheral Nerve Gaps
(Armin Kraus, Department of Plastic, Aesthetic and Hand Surgery, University Hospital of Magdeburg, Germany)

Chapter 3. Therapeutic Investigation of Ginsenoside Rb1 and Phosphoramidon (Endothelin Converting Enzyme Inhibitor) in the Zebrafish Model of Diabetic Retinopathy
(Arunachalam Muthuraman, Thiagarajan Venkataratinakumar, Nallupillai Paramakrishnan, Muthusamy Ramesh, Sumeet Kumar Singla and Thimmaiah Madesh, Pharmacology Unit, Faculty of Pharmacy, AIMST University, Semeling, Bedong, Kedah Darul Aman and Malaysia)

Chapter 4. Chhaya: The Nonsteroidal, Non-Hormonal, Once-A-Week Oral Contraceptive Pill
(Man Mohan Singh, Endocrinology Division, CSIR-Central Drug Research Institute, Lucknow, India)

Chapter 5. Signal Transduction Interplay of Doxorubicin Resistance: Selected New Developments
(Eric Chekwube Aniogo, Blassan P. George and Heidi Abrahamse, Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, Doornfontein, South Africa)

Chapter 6. Doxorubicin Increases Oxidative Damage as Consequence of Their Side Effects in Clinical Disorders
(David Calderón Guzmán, Maribel Ortíz Herrera, Hugo Juárez Olguín, Lulú Sánchez Reyes and Norma Osnaya Brizuela, Laboratory of Neurosciences, Instituto Nacional de Pediatría, Mexico City, Mexico, and others)

Chapter 7. Prevention and Treatment of Urinary Incontinence during Pregnancy and after Childbirth: The Role of Pelvic Floor Muscle Training
(Costanzi Flavia, Ilary Ruscito, Bellati Filippo, Maria Paola De Marco and Donatella Caserta, Department of Surgical and Medical Sciences and Translational Medicine, Sant' Andrea University Hospital, Sapienza University of Rome, Rome, Italy)

Chapter 8. Interactions of Probiotics and Lactic Acid Bacteria with Heat Shock Proteins, Apoptosis, and Intracellular Signaling Pathways
(Özge Kahraman Ilikkan, PhD, Başkent University, Kahramankazan Vocational School, Food Quality Control and Analysis Program, Ankara, Turkey)

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