Advances in Medicine and Biology. Volume 163

Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology
BISAC: MED000000

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Advances in Medicine and Biology. Volume 163 begins by discussing lipidomics, a newly emerging field of biomedical research that uses a mass spectrometry-based tool for the quantitative and qualitative analysis of complex lipids in the biological system.

Following this, the authors analyze basic aspects of the cellular processes involved in olfactory signal transduction, focusing on the neurogenic processes of neuronal stem cells from the olfactory neuroepithelium.

Recent information from several experimental studies is presented highlighting the application of CCl4 as an inducer of pathophysiological changes in key organs of the body.

The preparation, advantages and multi-functionality of nano emulsions is reviewed in the context of their potential applications in targeted drug delivery.

The existing preclinical and clinical studies carried out with sacubitril-valsartan (and other drugs with similar pharmacological mechanisms) in heart failure and hypertensive patients are described.

The authors go on to explore monoclonal antibodies targeting multiple myeloma, a plasma cell neoplasia accounting for 10% of hemopoietic neoplasias.

The closing study examines the various approaches for mitral valve surgery, comparing and contrasting the benefits and drawbacks of each.
(Imprint: Nova Medicine and Health)

Preface

Chapter 1. Lipidomics in Human Pathophysiology: Progress and Prospects
(Himanshu Sharma, Saif Hameed and Zeeshan Fatima, Amity Institute of Biotechnology, Amity University Haryana, Gurugram, Haryana, India)

Chapter 2. Calcium and cAMP Signaling in Olfactory Epithelium Cells Obtained from Patients Diagnosed with Psychiatric Disorders
(Zuly A. Sánchez-Florentino, Edgar Flores-Soto, Luis M. Montaño, Ramón Alvarado-Alvarez, Elizabeth Guarneros-Bañuelos, Bettina Sommer, Arnoldo Aquino-Gálvez, Marcela Valdés-Tovar, Bianca S. Romero Martínez, Gloria Benítez-King and Héctor Solís-Chagoyán, Laboratorio de Neurofarmacología, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, México, and others)

Chapter 3. CCl4 Intoxication: Prophylatic and Therapeutic Properties of Some Medicinal Plants
(Sónia M. R. Oliveira, PhD, Elsa Dias, PhD, Henrique M. A. C. Fonseca, PhD, Helena Silva, PhD, Ana Paula Girol, PhD, Bechan Sharma, PhD, and Maria de Lourdes Pereira, PhD, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia, and others)

Chapter 4. Nano Emulsion as a Targeted Drug Delivery: An Update
(Usman Ali Ashfaq, Arooj Anwaar, Anam Javaid, Abdaal Ali, Syeda Anam Akram, Areej Fatima and Shazma Kanwal, Department of Bioinformatics and Biotechnology, Government College University Faisalabad, Pakistan)

Chapter 5. Sacubitril-Valsartan Use in Kidney Disease
(Nicolas Roberto Robles, Jose Carlos Arevalo and Guillermo Gervasini, Department of Nephrology, Badajoz University Hospital, Badajoz, Spain, and others)

Chapter 6. Monoclonal Antibody Treatments in Multiple Myeloma
(Semra Paydas, MD, Faculty of Medicine, Department of Medical Oncology, Cukurova University, Adana, Turkey)

Chapter 7. Mitral Valve Surgery by Means of Minimally Invasive Right Mini-Thoracotomy Compared with Standard Sternotomy: Technical Surgical Aspects, Clinical Results in the Current Era
(Paolo Nardi, MD, Calogera Pisano, MD, Fabio Bertoldo, MD, Antonio Scafuri, MD, Carlo Bassano, MD, Dario Buioni, MD, Claudia Altieri, MD, Dionisio F. Colella, MD, and Giovanni Ruvolo, MD, Cardiac Surgery Division, Tor Vergata University Hospital, Rome, Italy, and others)

Index

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