Advances in Medicine and Biology. Volume 162

Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology
BISAC: MED000000

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Advances in Medicine and Biology. Volume 162 opens with an assessment of the modern available data, as well as the results from the authors’ own research, on the neurotropic effects of amino acid L-arginine. The effects of L-arginine and some arginine-containing oligopeptides on pain and pain-induced behavior in rats are examined.

Depending on their binding to activate specific receptors, antagonists have selective functions. As such, this compilation details their specificity, mode of interactions and their usefulness and drawbacks for humans.

Next, a review on how CD14 interacts with different ligands is discussed, particularly focusing on how CD14 consequently transduces the signaling to induce some relevant diseases.

The authors also review some trends in the treatment of anxiety with natural compounds and transition metal-catalyzed couplings for the synthesis of new drugs with anxiolytic properties. Natural products have been widely used in the treatment of anxiety disorders and as a source of bioactive heterocyclic compounds.

Methods for improving the perception and attitude of health workers towards generic drugs are proposed, such as putting forward generic drugs as one of the learning topics in college curricula, and conducting scientific discussions and conferences on generic drugs through professional organizations.

The penultimate study comprehensively reviews the clinicopathological features of lipoblastomas and emphasizes the importance of accurate diagnosis and the differentiation of lipoblastomas from other histologically similar lipomatous neoplasms.

The closing study proposes that the relaxant effects of flavone may be due to the inhibition of enzyme activities and intracellular Ca2+ of the trachealis after increasing these two cyclic nucleotides.
(Imprint: Nova Medicine and Health)

Preface

Chapter 1. Neurotropic Effects of Amino Acid L-Arginine and Arginine-Containing Oligopeptides
(Liudmila A. Severyanova, MD, and Dmitry V. Plotnikov, MD, Department of Pathophysiology, Kursk State Medical University, Kursk, Russia, and others)

Chapter 2. Agonists: Types and Activity
(Pratibha Srivastava and Ritu Mamgain, Bioprospecting Group, Agharkar Research Institute, Pune, Maharashtra, India)

Chapter 3. CD14: Interactions and Functions
(Zhenghao Wu and Ping Lei, Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, and others)

Chapter 4. An Approach to the Natural Anxiolytics and Catalytic Functionalization
(Marianela Saldías, Gabriela Valenzuela-Barra, Marcelo Peña-Cerda and Eduardo Sobarzo-Sánchez, Instituto de Investigación e Innovación en Salud, Facultad de Ciencias de la Salud, Universidad Central de Chile, Santiago, Chile, and others)

Chapter 5. How to Improve the Perception and Attitude of Health Workers towards Generic Drugs
(Zulfiayu Sapiun, Department of Pharmacy, Health Polytechnic of Gorontalo, Indonesia)

Chapter 6. Lipoblastoma
(Kenneth Y. Y. Kok, Pengiran Anak Puteri Rashidah Sa’adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Bandar Seri Begawan, Brunei)

Chapter 7. Flavone via Phosphodiesterase Inhibition Leftward Shifted the Log Concentration-Relaxation Curves of Forskolin and Nitroprusside in Isolated Guinea-Pig Trachea
(Wun-Chang Ko, PhD, and Junn-Lain Chen, Department of Pharmacology, Taipei Medical University, Taipei, Taiwan)

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