Advances in Medicine and Biology. Volume 158

Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology
BISAC: MED000000

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Advances in Medicine and Biology. Volume 158 reviews the evolution of the network-based approaches to understanding comorbidities. These approaches can reveal underlying molecular mechanisms by identifying perturbations in shared proteins or protein-protein interactions as the cause of comorbidity.

Subsequently, the authors discuss radiculopathy, a painful condition in which conduction along a spinal nerve is blocked resulting in objective neurologic signs such as numbness or weakness or in compromised blood supply to a spinal nerve root, resulting in paresthesia.

This collection also provides a practical reference for several aspects of blunt craniofacial trauma management, including clinical presentation recognition, the classification of injuries, and the indications for urgent interventions.

36 structures of VEGFR-2 are available in the protein data bank. In the penultimate chapter, a visual analysis is carried out for the identification of the conformation. 31 structures were present in the DFG-out conformation.

The concluding chapter provides useful information about folate and its significant role in health maintenance and disease prevention, as well as dietary recommendations to researchers in basic sciences, public health, and clinical medicine.
(Imprint: Nova Medicine and Health)

Preface

Chapter 1. A Review of Network Medicine Approaches to Understand Comorbidity
(Joaquim Aguirre-Plans, Janet Piñero, Daniel Aguilar, Emre Guney, Ferran Sanz2 Laura I. Furlong, Narcis Fernandez-Fuentes and Baldo Oliva, Structural Bioinformatics Group, Research Programme on Biomedical Informatics, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain, and others)

Chapter 2. Radiculopathy: Causes, Diagnosis and Treatment
(Dimitar Tonev and Stoika Radeva, Department of Anaesthesiology and Intensive Care, Department of Physical Medicine and Rehabilitation, Medical University of Sofia, Sofia, Bulgaria)

Chapter 3. Management of Blunt Craniofacial Trauma
(Thao Wolbert, MD, Rahman Barry, MD, Adel Faltaous, MD, and David Denning, MD, Department of Surgery, Marshall University, Huntington, WV, US)

Chapter 4. Comparative Studies on Ligand- and Structure-Based Pharmacophores of VEGFR-2: An Approach to Consider Kinase Flexibility
(Urmila J. Joshi, PhD, Heena R. Bhojwani and Khushboo V. Begwani, Department of Pharmaceutical Chemistry, Principal K. M. Kundnani College of Pharmacy, Mumbai, Maharshtra, India)

Chapter 5. General Properties of Natural and Synthetic Forms of B9 Group Vitamins and Their Effects on Health
(M. Khadem Sadigh, M. S. Zakerhamidi and E. Seyedrezazadeh, Department of Physics and Optical Engineering, University of Bonab, Bonab, Iran, and others)

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