Advances in Medicine and Biology. Volume 155

Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology
BISAC: MED000000

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Advances in Medicine and Biology. Volume 155 reviews whether the non-surgical and non-pharmacological interventions commonly used for knee osteoarthritis patients are effective and, if effective, which ones are the most effective. For this, randomized controlled trials were identified through electronic databases.

Following this, the authors discuss how the early identification of target subjects who are at high cardiometabolic risk is important for critical lifestyle interventions and pharmacological management strategies.

Additionally, they discuss the diversity, biotechnological applications and sustainable bioproduction of chitinases enzyme from Streptomyces origin, as well as their properties, production and potential applications in the industrial and biotechnological spheres.

New strategies such as the use of atomic force microscopy, the isolation of cardiomyocytes, primary culturing in different types of substrates as well as transcriptomic studies are enabling the understanding of how these cells can be affected by different pathologies. As such, in this compilation these issues are updated by analyzing how new approaches to basic aspects of the structure and physiology of cardiomyocytes can be of clinical relevance.

This collection also discusses chitotriosidase and acidic mammalian chitinase belonging to the chitinase family. This family includes 18 chitinases united by the features of their molecular structure.

Degenerative lumbar spondylolisthesis is a common, multifactorial process also associated with aging, which frequently causes central canal stenosis. Several types of interbody fusion procedures that may treat of degenerative lumbar spondylolisthesis are examined, particularly lateral lumbar interbody fusion.

The final chapter explores the role surgical intervention plays in the diagnosis, staging, and treatment of malignant pleural mesothelioma.
(Imprint: Nova Medicine and Health)

Preface

Chapter 1. Metabolic Disturbances in Women with Polycystic Ovary Syndrome
(Gokce Anik Ilhan, Department of Obstetrics and Gynecology, Marmara University, Istanbul, Turkey)

Chapter 2. Streptomyces Chitinase: Diversity, Biotechnological Applications and Sustainable Bioproduction
(Abhik Mojumdar, Himadri Tanaya Behera and Lopamudra Ray, School of Biotechnology, Kalinga Institute of Industrial Technology, Bhubaneswar, Odisha, India, and others)

Chapter 3. New Approaches to the Morphophysiological Study of Cardiomyocytes with Clinical Relevance
(Gerardo Romanelli, PhD, Rocío Varela, Inés Rauschert, Camila Espasandín and Juan Claudio Benech, PhD, Laboratorio de Señalización Celular y Nanobiología, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay, and others)

Chapter 4. Biological Functions and Pathological Roles of Chitinases: A Comparison between Humans and Mice
(T. A. Korolenko, T. P. Johnston, A. B. Shintyapina, A. B. Pupyshev, E. Korolenko and N. V. Goncharova, Institute of Physiology and Basic Medicine, Novosibirsk, Russia, and others)

Chapter 5. LLIF for the Treatment of Degenerative Spondylolisthesis
(Daniel Arnoni, Rodrigo Amaral, Gabriel Pokorny, Rauqel Rodrigues, Thyago Guirelli and Luiz Pimenta, Instituto de Patologia da Coluna, São Paulo, São Paulo, Brazil)

Chapter 6. Surgery in Malignant Pleural Mesothelioma: Extra-Pleural Pneumonectomy – A Critical Appraisal
(Luca Bertolaccini, MD, PhD, and Lorenzo Spaggiari, MD, PhD, Division of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy, and others)

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