Advances in Medicine and Biology. Volume 142

Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology
BISAC: MED000000



Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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The authors of the opening chapter of Advances in Medicine and Biology. Volume 142 provide recommendations and tips to assist medical oncologists, hematologists and clinicians in investigating and managing early catheter malfunction.

The aim of the following chapter is to ease prompt recognition and management of central venous catheter-related infectious outbreaks, as they may severely jeopardize the outcome of infected patients

Next, the placement and maintenance of central venous access devices in the neonatal patient population, with particular regard to umbilical catheters and peripherally inserted central catheters is examined.

The authors go on to investigate whether low trabecular bone score during adolescence is predictive of increased fracture risk during adulthood, as well as whether recovery may result in correction of compromised microarchitecture.

A summary of the involvement of miRNAs in different beta-thalassemia variants, their association in expression of various globin types, (especially gamma-globin) and their implications as prognostic and therapeutic markers in beta-thalassemia are presented.

Additionally, an account is provided on various commonly used monoclonal antibodies targeting the transferrin receptor. The authors also discuss the mechanisms through which monoclonal antibodies targeting the transferrin receptor have been employed to deliver drugs, enzymes, toxins and cytokines to treat various neurological cancers, Alzheimer’s disease, Parkinson’s disease, lysosomal storage diseases and cerebral ischemia.

This compilation assesses the use of clarithromycin in the long-term treatment of chronic rhinosinusitis with polyps after endoscopic sinus surgery, showing that a low-dose clarithromycin use for a period of one month can improve patient complaints.
The role of aromatase inhibitors for the treatment of endometriosis is subsequently described.

Numerous surgical procedures have been reported in patients with situs inversus. The penultimate chapter provides insight regarding laparoscopic surgeries for various indications in patients with situs inversus, along methods to address them.

The final chapter improves upon the current knowledge of Stenotrophomonas maltophilia, which is a gram-negative rod and typical soil inhabitant bacteria.

(Imprint: Nova Medicine and Health)


Chapter 1. Central Venous Catheters (CVCs) Early Dysfunction and Misplacement
(Davide Mauri, Georgia Zafeiri, LamprianiTsali, Melina Yerolatsite, George Zarkavelis, Lida Fereniki Kostadima, Panagiotis Ntellas, Areti Sofia Derveni, and George Pentheroudakis, Department of Medical Oncology, University Hospital of Ioannina, Ioannina, Greece)

Chapter 2. Central Venous Catheter Infection Outbreaks in Clinical Practice: Investigation and Management
(Davide Mauri, Melina Yerolatsite, George Zarkavelis, Lampriani Tsali, Georgia Zafeiri, Dimitrios Petrakis, Panagiotis Ntellas, Ioanna Mouzaki, and George Pentheroudakis, Department of Medical Oncology, University Hospital of Ioannina, Ioannina, Greece)

Chapter 3. Central Venous Access in the Neonate
(Matilde M. Ciccia, MD, Neonatal Intensive Care Unit, Department of Women’s and Children’s Health, Maggiore Hospital, Bologna, Italy)

Chapter 4. Trabecular Bone Score in Children
(Yael Levy-Shraga, and Dalit Modan-Moses, Pediatric Endocrinology Unit, The Edmond and Lily Safra Children's Hospital, Chaim Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel, and others)

Chapter 5. MicroRNAs in Beta-Thalassemia: Pathogenesis, Diagnosis and Treatment
(Sankha Subhra Das, and Nishant Chakravorty, School of Medical Science and Technology, Indian Institute of Technology Kharagpur, West Bengal, India)

Chapter 6. Antibody-Mediated Targeting of Transferrin Receptor
(Shaluah Vijeth, Geetha B. Heggannavar, and Mahadevappa Y. Kariduraganavar, Department of Chemistry, Karnatak University, Dharwad, India)

Chapter 7. The Pharmacological Guide to Clarithromycin
(Pietro Abita, MD, Francesco Galletti, Bruno Galletti, Francesco Gazia, MD, Rocco Bruno, Francesco Martines, Frank Rikki Canevari, Francesco Dispenza, MD, Francesco Freni, and Federico Sireci, MD, Department of Otorhinolaryngology, University of Messina, Italy, and others)

Chapter 8. Aromatase Inhibitors in the Treatment of Endometriosis: Evidence and Perspectives
(Simone Ferrero, Carolina Scala, and Fabio Barra, Academic Unit of Obstetrics and Gynecology, DINOGMI, University of Genova, IRCCS Ospedale Policlinico San Martino, Genova, Italy)

Chapter 9. Laparoscopic Surgery in Situs Inversus
(Pankaj Kumar, Tushar S Mishra, and Siddhant Sarthak, Department of General Surgery, AIIMS Bhubaneswar, Odisha, India)

Chapter 10. Biotechnology Application of Stenotrophomonas maltophilia
(Zhen Fang, School of Environment, Jiangsu University, Zhenjiang, China)


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