Advances in Medicine and Biology. Volume 114

Leon V. Berhardt (Editor)

Series: Advances in Medicine and Biology
BISAC: MED106000



Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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The chapters in this volume present the latest developments in medicine and biology. Chapters One focuses on the synthesis of bisphosphonates and its biomedical applications. Chapter Two reviews polymeric nano-vectors based siRNA delivery. Chapter Three discusses the use of thrombophilia and pharmacological throboprophylaxis screening in women. Chapter Four provides insights into Geobacillus species through an overview of the model strain HTA426. Chapter Five examines how glycans provide molecular recognition motifs which regulate endoplasmic protein folding, transport, lysosomal targeting, and also how they are used by pattern recognition receptors in pathogen surveyance and innate immunity. Chapter Six discusses the effect of dehydroepiandrosterone (DHEA) on diabetes, obesity, and atherosclerosis. Chapter Seven discusses the various classifications, clinical features, diagnosis, and management options of juvenile idiopathic arthritis (JIA). Chapter Eight studies several surgical approaches for knee arthroplasty with their relevant advantages and disadvantages. Chapter Nine explores the antioxidant potential of lipoic acid in ameliorating the oxidative stress produced during lung carcinogenesis.
(Imprint: Nova Biomedical)


Chapter 1. Synthesis of Bisphosphonates and their Biomedical Applications
Blessing A. Aderibigbe (Department of Chemistry, University of Fort Hare, Alice Campus, Eastern Cape, South Africa)

Chapter 2. Polymeric Nano-Vectors Based siRNA Delivery: A Blooming Field Towards Better Therapeutics
R. Mankamna Kumari, Nikita Sharma, Nidhi Gupta, Ramesh Chandra, and Surendra Nimesh (Department of Biotechnology, School of Life Sciences, Central University of Rajasthan, Ajmer, Rajasthan, India, and others)

Chapter 3. The Use of Thrombophilia and Pharmacological Thromboprophylaxis Screening in Women: The Benefits of the RIETE Registry
Pierpaolo Di Micco, Angeles Blanco Molina, Donatella Colaizzo, Francesco Dentali, Andrea Fontanella, Matteo Giorgi Pierfranceschi, Elvira Grandone, Benjamin Brenner, and Manuel Monreal (Emergency Room, Medicine Department, Fatebenefratelli Hospital of Naples, Italy, and others)

Chapter 4. Geobacillus kaustophilus HTA426: a Model Organism for Moderate Thermophiles
Hirokazu Suzuki (Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, Tottori, Japan)

Chapter 5. Glycans Provide Molecular Recognition Motifs Which Regulate Endoplasmic Protein Folding, Transport, Lysosomal Targeting, and are Used by Pattern Recognition Receptors in Pathogen Surveyance and Innate Immunity
James Melrose (Raymond Purves Bone and Joint Research Laboratory, Kolling Institute of Medical Research, Northern Sydney Local Health District, St. Leonards, New South Wales, Australia, and others)

Chapter 6. The Effects of Dehydroepiandrosterone (DHEA) on Diabetes Mellitus, Obesity, and Atherosclerosis
Kazutaka Aoki and Yasuo Terauchi (Internal Medicine, Kanagawa Dental University, Inaoka-cho, Yokosuka, Japan, and others)

Chapter 7. Juvenile Idiopathic Arthritis: New Hopes for an Old Malady
Shakeel Ahmed, Syed Rehan Ali and Anila Haroon (Aga Khan University Hospital, Karachi, Pakistan)

Chapter 8. Surgical Approaches in Knee Arthroplasty
Prasad Ellanti, Priyanka Ellanti and Thomas McCarthy (Department of Orthopaedics, St. James’s Hospital, Dublin, Ireland, and others)

Chapter 9. Enhancement of Antioxidant System by Lipoic Acid in Experimental Lung Tumorigenesis
Pandi Anandakumar, Thiruvengadam Devaki and Manickam Kalappan Vanitha (Department of Biochemistry, University of Madras, Guindy campus, Chennai, India, and others)


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