Samiye Esila (Editor)

Series: Microbiology Research Advances
BISAC: MED052000; MED022090; MED071000
DOI: https://doi.org/10.52305/PHWP7657

This volume includes eight chapters that detail advances in medical microbiology and antimicrobial research. Chapter 1 examines the global burden and biological mechanisms of AMR, with emphasis on resistance-driving factors, priority pathogens, and the role of biofilms in treatment failure and healthcare-associated infection. Chapter 2 examines Escherichia coli (E. coli) as an ecologically versatile actor whose trajectory across agro-environmental systems is shaped by the interplay of habitat structure, selective pressure, and evolutionary capacity. Chapter 3 comprehensively evaluates the antimicrobial effects of different classes of phytochemicals, namely flavonoids, alkaloids, tannins, terpenoids, and saponins, against bacteria, fungi, and viruses, and to elucidate the underlying biochemical mechanisms of action. Chapter 4 explores the biology of cryptococcal biofilms, the regulatory genes involved, and the emerging field of biofilm inhibitors, including essential oils and synthetic molecules. Chapter 5 examines the transition from traditional antimicrobial mechanisms to the development of nanomaterial-based solutions. Chapter 6 tests different one-pot approaches to obtaining combined AmB/nanometal preparations. Chapter 7 provides an overview of the molecular features of cryptococcosis obtained through high-throughput analyses, along with a discussion of the application of omics techniques to understand such molecular apparatus. Finally, chapter 8 explores the profound technological transformation currently redefining the field of medical microbiology, focusing on the adoption of sophisticated automated devices within the framework of The Age of Automated Systems: Technology, Ethics, and Autonomy.

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