Advances in Marine Biology. Volume 3


Adam Kovács and Patrik Nagy (Editors)

Series: Advances in Marine Biology
BISAC: SCI039000

Advances in Marine Biology. Volume 3 begins by focusing on some novel compounds having antioxidant, antimicrobial, anti-inflammatory, anticancer and other bioactive properties identified and isolated from marine sponges, which could serve as leads for drug discovery. The authors also discuss the factors that contribute to new discoveries and the challenges associated with translating marine sponge-derived compounds into clinical trials. The advances that may further expand the promise of drug discovery from marine sponges are also examined. Following this, the authors present current information about Hox-genes in polychaetes and make some cautious assumptions about the ancestral functions of the Hox-cluster. The basic plane and evolution of bilateral animals (Bilateria) are closely associated with Hox-genes. These genes usually exist in the genome in the form of the aforementioned clusters, gene complexes with a conservative position of individual genes inside them.

Marine biotoxins are examined, specifically their correlation with of harmful algal blooms (HABs) which can accumulate in seafood products. This can have severe consequences on both the fishery industry and consumer health, as most marine biotoxins are not destroyed by food technologies like freezing or cooking, and their presence cannot be perceived because they give no specific taste, flavor or smell to food. The subsequent article contains a study on adaptation to environmental salinity alterations in the White Sea mussel Mytilus edulis, with its research having been conducted for several years and involving both long-term acclimation and exposure to stress salinity. A series of experiments were conducted in order to deduce the mussels’ capacity to adapt to environmental salinity changes, especially in terms of cell and molecular mechanisms of salinity adaptation. This compilation also presents a preliminary work within a large scale research program on H. diversicolor in different estuaries with the PNETOX Program ‘National Program of Ecotoxicology’. In the framework of the French National Program of Ecotoxicology, environmental quality was assessed in the multi-polluted Seine Estuary and the comparatively clean Authie Estuary, France (2002-2004), by determining contaminant levels in water, sediments and the infaunal worm H. diversicolor. The experiments were carried out concurrently in spring 2007 using a common protocol.


Table of Contents

Table of Contents


Chapter 1. Natural Products from Marine Sponges: Current Status and Future Potential for Novel Drugs
(Rima Beesoo, Vidushi S. Neergheen-Bhujun, Ranjeet Bhagooli, and Theeshan Bahorun, Department of Biosciences and Ocean Sciences, Faculty of Science, University of Mauritius, Réduit, Republic of Mauritius, and others)

Chapter 2. Hox-Genes in the Ontogenesis of Polychaetes
(Milana A. Kulakova, Department of Embryology, Saint Petersburg State University, Saint Petersburg, Russia)

Chapter 3. Novel Fibrinogenolytic Metalloprotease from the Antarctic Scallop (Adamussium colbecki)
(Nataliia G. Raksha, Tetiana I. Halenova, Tetiana B. Vovk, Tetiana V. Ishchuk, Oleksii M. Savchuk, and Lydmila I. Ostapchenko, Educational and Scientific Center “Institute of Biology and Medicine” Taras Shevchenko National University of Kyiv, Kyiv, Ukraine)

Chapter 4. Investigation of Marine Biotoxins and Human Toxicity
(Pierina Visciano and Maria Schirone, Faculty of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy)

Chapter 5. Dynamics of the Stress Protein Content in the White Sea Mussel Mytilus edulis L in Course of Salinity Adaptation
(Yulia I. Podlipaeva and Andrew V. Goodkov, Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia)

Chapter 6. The Key Role of the Species Hediste diversicolor (Polychaeta, Nereididae) in Estuarine Ecosystems
(Patrick G. Gillet, PhD, Mohammed Mouloud, PhD and Catherine Mouneyrac, PhD, Department of Biology Environment, UCO University, Angers, France)



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