Advances in Health and Disease. Volume 73


Lowell T. Duncan (Editor)

Series: Advances in Health and Disease
BISAC: MED000000

This volume contains eight chapters that detail advances in health and disease. Chapter One provides a comprehensive review on the physicochemical, pharmacological and pharmacokinetic properties of paracetamol. Chapter Two reports about simulated microgravity, its effects on different organs of a healthy body, and its role in various types of diseases. Chapter Three discusses vitamin D and its relationship with nephrotoxic drugs. Chapter Four describes the epidemiology, pathogenesis, diagnosis (classification), and treatment of patients with hypertrophic pachymeningitis related to antineutrophil cytoplasmic antibody associated vasculitis. Chapter Five reviews the current scientific data regarding the genetic causes and novel genes involved in various abnormalities of sex development disorders. The authors in Chapter Six report their clinical experience with poly-methyl-methacrylate for a novel in vivo bone defect closure in various neurosurgical operations. Chapter Seven provides a detailed comparison of multiple studies that were conducted using a variety of approaches with the goal of preventing drug-drug interaction (DDI) responses, which are a form of adverse pharmaceutical reactions. Lastly, Chapter Eight covers upcoming nanotechnological methods and updates on liposomal research.

Table of Contents


Chapter 1. Paracetamol: Physicochemical and Pharmacokinetic Properties
Selma Sahin, PhD, Fatma Kir and Meryem Kilincarslan
Department of Pharmaceutical Technology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey

Chapter 2. Microgravity and Its Effect on the Human Body
Medha, Abhipsa Debnath and Amit Roy
Department of Biotechnology, Savitribai Phule Pune University, Pune, India

Chapter 3. Drug-Induced Nephrotoxicity and Vitamin D Status
Daniele Canale¹, PhD, Ana Carolina de Bragança², PhD, Rildo Aparecido Volpini², PhD and Janaína Garcia Gonçalves³, MD
¹Laboratorio de Investigacao Medica 12 (LIM12), Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
²Laboratorio de Investigacao Medica 12 (LIM12), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
³Nefrostar Clinic, Dialysis Center, São Paulo, Brazil

Chapter 4. Hypertrophic Pachymeningitis Related to ANCA-Associated Vasculitis
Yasuhiro Shimojima, MD, PhD
Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan

Chapter 5. The Genetics of Disorders of Sex Development
Neslihan Hekim¹, PhD and Sezgin Gunes¹,², PhD
¹Ondokuz Mayis University, Medical Faculty, Department of Medical Biology, Turkey
²Ondokuz Mayis University, Graduate Institute, Department of Molecular Medicine, Turkey

Chapter 6. Neurosurgical Applications of Biopolymers in Clinical Practices: The Cranial Bone Reconstruction with Poly-Methyl-Methacrylate
Tomaz Velnar¹, Roman Bosnjak¹ and Lidija Gradisnik²
¹Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia
²Institute of Biomedical Sciences, Medical Faculty Maribor, Maribor, Slovenia

Chapter 7. Drug-Drug Interaction Prognosis: A Comprehensive Analysis of Methods to Minimize Adverse Drug Effects
G. L. Swathi Mirthika, B. Sivakumar, V. Deepa and K. Abinaya
Department of Computing Technologies, School of Computing, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu, Tamil Nadu, India

Chapter 8. Liposome: Advances in Research and Applications
Rudra Narayan Sahoo¹ and Snehanjana Biswal²
¹School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India
²School of Pharmacy and Life Sciences, Centurion University of Technology and Management, Bhubaneswar, Odisha, India


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