Advances in Health and Disease. Volume 72


Lowell T. Duncan (Editor)

Series: Advances in Health and Disease
BISAC: MED000000

This volume contains eleven chapters that detail advances in health and disease. Chapter One examines the role of demethylases in regulation, with an emphasis on existing and upcoming treatments that focus on this enzyme class. Chapter Two provides a multiparametric acoustic analysis of voice assessments. Chapter Three discusses the clinical applications and outcomes of splenectomies. Chapter Four analyzes the safety of laparotomy compared with the effectiveness of the procedure. Chapter Five proposes a multiple-factor regression mathematical model for predicting the diabetic foot ulcer development risk. Chapter Six presents the risk factors, indications, and management of relaparotomy after cesarean section delivery. Chapter Seven elaborates on the critical role of Sphingosine-1-phosphate (S1P) in wound healing cascades, with the goal of advancing the application of S1P-targeted therapeutic strategies in clinical treatment. Chapter Eight provides an overview of recent innovative developments, directions, and trends in the field of Paracetamol. Chapter Nine explains the function of paracetamol in treating dental pain and compares the risks and advantages of its use. Chapter Ten provides standard statistical rules that thoracic surgeons unfamiliar with statistical modeling analysis should follow. Finally, Chapter Eleven explains a study that applied next-generation sequencing and subsequent data analysis to investigate several food-borne non-typhoidal Salmonella strains.

Table of Contents


Chapter 1. Protein Demethylases: The Characterization and Current Focus on the Development of
Targeted Therapeutics
Nashira H. Ridgeway, Mullen Boulter, Matt Hoekstra and Kyle K. Biggar
Institute of Biochemistry, Carleton University, Ottawa, Ontario, Canada

Chapter 2. A Multiparametric Acoustic Analysis of Voice Assessments
Srushti Shabnam1 and Pushpavathi M.2
Nitte Institute of Speech and Hearing, Nitte Deemed to be University,Mangalore, Karnataka, India
2All India Institute of Speech and Hearing, Mysore, Karnataka, India

Chapter 3. Splenectomy: Clinical Applications and Outcomes
Prasanna Ramana Arumugaswamy, Devender Singh, Yashwant Singh Rathore and Sunil Chumber, HOD
Department of Surgical Disciplines, AIIMS, New Delhi, India

Chapter 4. Laparotomy: From Efficacy to Safety
Simões Júlia1, Braga Geórgia1 and Bagatini Margarete2, MD
1Medical School, Federal University of Fronteira Sul, Chapecó, Santa Catarina, Brazil
2Graduate Program in Biomedical Sciences – Federal University of Fronteira Sul, Chapecó, Santa Catarina, Brazil

Chapter 5. Diabetic Foot Ulcer Risk Factors and Forecasting Its Development in Patients with Type 2 Diabetes
T. G. Bakaliuk, N. R. Makarchuk, A. S. Sverstiuk and H. O. Stelmakh
I. Horbachevsky Ternopil National Medical University, Ministry of Health of Ukraine

Chapter 6. Relaparotomy After Cesarean Section: Risk Factors, Indication, and Management
Cipta Pramana
Obstetrics and Gynecology Department of KRMT Wongsonegoro Hospital Semarang, Indonesia
Faculty of Medicine Universitas Islam Negeri Walisongo Semarang, Indonesia

Chapter 7. Sphingosine-1-Phosphate as an Immunocyte Regulator and Novel Therapeutic Option
for Wound Healing
Zhiguo Ling1, Yuhan Wang2 and Yueqi Chen3
1Institute of Immunology, Third Military Medical University (Army Medical University), Chongqing, People’s Republic of China
2Institute of Burn Research, Southwest Hospital, State Key Lab of Trauma, Burn and Combined Injury, Chongqing Key Laboratory for Disease Proteomics, Third Military Medical University (Army Medical University), Chongqing, People’s Republic of China
3Department of Orthopedics, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, People’s Republic of China

Chapter 8. Innovative Developments, Directions, and Trends in the Field of Paracetamol
Neelkant Patil1, MDS, Surekha Waghanna2, PhD Scholar and Santosh R. Patil3, MDS, PhD
1Rajasthan Dental College and Hospital Jaipur Rajasthan, A constituent unit of Nirwan University, Jaipur, India
2National Institute of Medical Sciences, NIMS University Rajasthan Jaipur, India
3Healthminds Consulting Pvt Ltd., Bengaluru, India

Chapter 9. The Role of Paracetamol in Relieving Dental Pain: Benefits Versus Risks
Dr Santosh R. Patil, MDS, PhD
Senior medical writer and reviewer, Healthminds Consulting Pvt Ltd. Bengaluru, India

Chapter 10. The Statistical Modelling Minimum for Thoracic Surgeons
Luca Bertolaccini1, MD, PhD, FCCP, Monica Casiraghi1,2, MD, PhD, Cristina Diotti1, MD, Clarissa Uslenghi1, MD, Andrea Cara1, MD, Francesco Petrella1,2, MD, PhD and Lorenzo Spaggiari1,2, MD, PhD
1Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy
2Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy

Chapter 11. The Phylogenetic Study of Food-Borne Salmonella Strains with SNP Analysis Based on Core Genome Sequences Elaborated with Next Generation Sequencing
Ben Hassena Amal1, Julie Haendiges2, Narjol Gonzalez-Escalona2, Sonda Guermazi1 and Mariam Siala1,3
 1Department of Life Sciences, Research Laboratory of Environmental Toxicology-Microbiology and Health, Faculty of Sciences, University of Sfax, Sfax, Tunisia
2Division of Microbiology, Office of Regulatory Science, Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland, USA
3Department of Biology, Preparatory Institute for Engineering Studies of Sfax, University of Sfax, Tunisia



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