Advances in Health and Disease. Volume 63


Lowell T. Duncan (Editor)

Series: Advances in Health and Disease
BISAC: MED000000

This book contains nine chapters highlighting advances in health and disease. Chapter One reviews ubiquitin-dependent proteolysis as a therapeutic strategy. Chapter Two is a review of the analytical methodology of ginsenosides and their bioactive properties. Chapter Three explores the management of latent tuberculosis in pregnant, HIV-positive women. Chapter Four focuses on melioidosis pneumonia. Chapter Five explains the importance of DNA methylation in the body. Chapter Six examines the structural pharmacology of antiarrhythmic drug interaction with voltage-gated sodium channels. Chapter Seven explores chemical fractionation and the health risks of heavy metals in PM2.5. Chapter Eight reviews attempts to establish a local diagnostic reference level for adult computed tomography scans in hospitals and diagnostic centers in Addis Ababa, Ethiopia. Finally, Chapter Nine explores theory-based educational and behavioral interventions to improve oral anticoagulant adherence.

Table of Contents


Chapter 1. Ubiquitin-Dependent Proteolysis, a Therapeutic Strategy: An Interface between Health and Disease
Rajiv Kumar¹,², Magali Cucchiarini³, Madan Thangavelu⁴, Moganavelli Singh⁵ and Punit Dhar⁶
¹University of Delhi, Delhi, India
²NIET, National Institute of Medical Science, India
³Center of Experimental Orthopaedics, Saarland University Medical Center and Saarland University, Homburg/Saar, Germany
⁴Single Cell & Single Molecule Genomics, Genome Mapping & Analysis Biotechnology, Cambridge, UK
⁵Nano-Gene and Drug Delivery Laboratory, Dept. of Biochemistry, School of Life Sciences, University of KwaZulu-Natal (Westville Campus), Durban, South Africa
⁶Department of Surgical Gastroenterology, AIIMS, Rishikesh, Uttarakhand, India

Chapter 2. Analytical Methodology of Ginsenosides: Their Health Benefits, Anticancer and Antidementia Activities: A Review
Chong-Zhi Wang¹, Samantha Anderson¹, Tomoe Ohta², Takuhiro Uto², I. Jung Lee³, Hiroyuki Tanaka⁴, Tung Nguyen Huu⁵, Chun-Su Yuan¹,⁶ and Yukihiro Shoyama²
¹Tang Center for Herbal Medicine Research, and Departments of Anesthesia & Critical Care, University of Chicago, Chicago, IL, USA
²Faculty of Pharmacy, Nagasaki International University, Huis Tenbosh, Sasebo, Nagasaki, Japan
³Yokohama University of Pharmacy, Matano-cho, Totsuka-ku, Yokohama, Kanagawa, Japan
⁴Faculty of Pharmaceutical Sciences, Sanyo-Onoda City University, Sanyo-Onoda, Yamaguchi, Yamaguchi, Japan
⁵Faculty of Medicine, Phenikaa University, Hanoi, Vietnam
⁶Committee on Clinical Pharmacology and Pharmacogenomics, The Pritzker School of Medicine, University of Chicago, Chicago, Illinois, USA

Chapter 3. Management of Latent Tuberculosis in Pregnant Women with HIV Infection
Jenna D. Theroux¹,², Hudson O. West¹, Hayley W. Hamilton¹, and Adriane B. Marino¹
¹Wingate University School of Pharmacy, Wingate University, Wingate, NC, US
²Eastowne Family Physicians, Charlotte, NC, US

Chapter 4. Melioidosis Pneumonia
Wattana Leowattana, MD, PhD
Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Chapter 5. The Importance of DNA Methylation in the Body
Deniz Karakçı
Department of Biochemistry, University of Tekirdag Namik Kemal, Faculty of Veterinary Medicine, Tekirdag, Turkey

Chapter 6. Structural Pharmacology of Antiarrhythmic Drug Interactions with Voltage-Gated Sodium Channels
Akihiko Sunami¹ and Tatsuo Munakata²
¹School of Pharmacy, Department of Pharmaceutical Sciences, International University of Health and Welfare, Otawara, Tochigi, Japan
²School of Pharmacy at Fukuoka, Department of Pharmaceutical Sciences, International University of Health and Welfare, Okawa, Fukuoka, Japan

Chapter 7. Chemical Fractionation and Health Risks of Heavy Metals in PM2.5
Dinesh Sah, Puneet Kumar Verma, K. M. Kumari and Anita Lakhani
Department of Chemistry, Dayalbagh Educational Institute, Dayalbagh, Agra (UP), India

Chapter 8. Establishment of a Local Diagnostic Reference Level (LDRL) for Adult Computed Tomography (CT) Scans in Hospitals and Diagnostic Centers in Addis Ababa, Ethiopia
Blein Mulugeta¹, Wondemu Geteye¹, Efrem Mengistu², Yenuse Molla¹, and Ali Beyene¹
¹Department of Medical Radiologic Technology, Addis Ababa University, Ethiopia
²Department of Physics, Dire-Dewa University, Ethiopia

Chapter 9. Theory-Based Educational and Behavioral Interventions to Improve Oral Anticoagulant Adherence
Rebecca J. Cope¹, and Harrison Sulkow²
¹The Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY, USA
²NYC Health & Hospitals, New York, NY, USA


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